Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 12/20 | 0.44 |
| ▸ | MMP9 | P14780 | 12/20 | 0.44 |
| ▸ | MMP3 | P08254 | 10/20 | 0.44 |
| ▸ | MMP13 | P45452 | 10/20 | 0.44 |
| ▸ | MMP1 | P03956 | 9/20 | 0.44 |
| ▸ | MMP7 | P09237 | 9/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381845 | 1.00 | KDM4E (0.49) | KDM4EMMP2MMP9MMP3MMP13 | |
| SCHEMBL8381843 | 1.00 | KDM4E (0.49) | KDM4EMMP2MMP9MMP3MMP13 | |
| SCHEMBL5789286 | 0.78 | CA2 (0.42) | KDM4EMMP2MMP9MMP3MMP13 | |
| SCHEMBL30447725 | 0.78 | CA2 (0.42) | KDM4EMMP2MMP9MMP3MMP13 | |
| SCHEMBL5839738 | 0.76 | KDM4E (0.49) | KDM4EMMP2MMP9MMP3MMP13 | |
| SCHEMBL29612792 | 0.76 | KDM4E (0.49) | KDM4EMMP2MMP9MMP3MMP13 | |
| SCHEMBL5839741 | 0.76 | KDM4E (0.49) | KDM4EMMP2MMP9MMP3MMP13 | |
| SCHEMBL13612445 | 0.74 | KDM4E (0.47) | KDM4EMMP2MMP9MMP3MMP13 | |
| SCHEMBL9115909 | 0.74 | KDM4E (0.47) | KDM4EMMP2MMP9MMP3MMP13 | |
| SCHEMBL7477399 | 0.74 | MMP2 (0.47) | KDM4EMMP2MMP9MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758317-A1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBIOCIDES | Novartis AG (CH) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995030651-A1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBIOCIDES | CIBA-GEIGY AG (CH) | 1995-11-16 | — | — | WO | disclosed |