Styrene

Styrene

SCHEMBL8746482

C=C[Si](OCC)(OCC)OCC.C=Cc1ccccc1

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
TSHR P16473 1/20 0.52
RELA Q04206 1/20 0.38
NR1I2 O75469 1/20 0.38
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
TP53 P04637 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
CHRNA7 P36544 3/20 0.33
CHRNB2 P17787 2/20 0.33
CHRNB4 P30926 2/20 0.33
CHRNA3 P32297 2/20 0.33
CHRNA4 P43681 2/20 0.33
HDAC8 Q9BY41 2/20 0.32
NFE2L2 Q16236 1/20 0.32
MAPT P10636 2/20 0.32
KDM4E B2RXH2 2/20 0.32
HPGD P15428 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL11245822 0.88 ALDH1A1 (0.40) ALDH1A1TSHRNR1I2MEN1KMT2A
Styrene SCHEMBL27960803 0.85 ALDH1A1 (0.38) ALDH1A1TSHRNR1I2MEN1KMT2A
Styrene SCHEMBL11800514 0.85 AKR1C3 (0.41) ALDH1A1TSHRNR1I2MEN1KMT2A
Styrene SCHEMBL28209933 0.85 ALDH1A1 (0.56) ALDH1A1TSHRRELANR1I2MEN1
Benzene SCHEMBL28249034 0.84
SCHEMBL8467968 0.84 ALDH1A1 (0.34) ALDH1A1TSHRMEN1KMT2ACHRNA7
SCHEMBL10707684 0.84 ALDH1A1 (0.39) ALDH1A1TSHRRELAMEN1KMT2A
Styrene SCHEMBL11793510 0.83 ALDH1A1 (0.39) ALDH1A1TSHRNR1I2MEN1KMT2A
Styrene SCHEMBL11801626 0.83 AKR1C3 (0.40) ALDH1A1TSHRNR1I2MEN1KMT2A
Styrene SCHEMBL9727042 0.83 ALDH1A1 (0.54) ALDH1A1TSHRRELANR1I2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0757522-A1 PROCESS FOR FRACTIONATING WHEY PROTEINS AND THE COMPONENTS SO OBTAINED VALIO LTD. (FI) 1997-02-12 EP disclosed
US-5571654-A Toner compositions with negative charge enhancing additives XEROX CORPORATION (US) 1996-11-05 US disclosed
US-5538829-A Toner compositions with zinc and boron charge enhancing additives XEROX CORPORATION (US) 1996-07-23 US disclosed
US-5532098-A Toner compositions with negative charge enhancing additives XEROX CORPORATION (US) 1996-07-02 US disclosed
WO-1995019714-A1 PROCESS FOR FRACTIONATING WHEY PROTEINS AND THE COMPONENTS SO OBTAINED VALIO OY (FI) 1995-07-27 WO disclosed
US-5409794-A Toner compositions with metal chelate charge enhancing additives XEROX CORPORATION (US) 1995-04-25 US disclosed
US-5391453-A Toner compositions with aluminum complex composite charge additives XEROX CORPORATION (US) 1995-02-21 US disclosed
US-5332636-A Toner compositions with aluminum negative charge enhancing additives XEROX CORPORATION (US) 1994-07-26 US disclosed
US-5302481-A Toner compositions with negative charge enhancing complexes XEROX CORPORATION (US) 1994-04-12 US disclosed
US-5300387-A Toner compositions with negative charge enhancing additives XEROX CORPORATION (US) 1994-04-05 US disclosed
US-5290651-A Toner compositions with zinc complex charge enhancing additives XEROX CORPORATION (US) 1994-03-01 US disclosed
US-5275900-A Toner compositions with metal complex charge enhancing additives XEROX CORPORATION (US) 1994-01-04 US disclosed
US-5238768-A Toner compositions with sulfone charge enhancing additives XEROX CORPORATION (US) 1993-08-24 US disclosed
EP-0189611-B1 PROCESS FOR THE CHROMATOGRAPHIC SEPARATION OF BIOLOGICAL MACROMOLECULES Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1989-04-12 EP disclosed
EP-0189611-A1 Process for the chromatographic separation of biological macromolecules Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1986-08-06 EP disclosed
EP-0029443-A4 PROCESS FOR COMPOSITE POLYMER BEADS. ICI AUSTRALIA LTD (AU) 1981-09-21 EP disclosed
EP-0029443-A1 PROCESS FOR COMPOSITE POLYMER BEADS. ICI AUSTRALIA LTD (AU) 1981-06-03 EP disclosed
WO-1980002687-A1 PROCESS FOR COMPOSITE POLYMER BEADS ICI AUSTRALIA LTD (AU) 1980-12-11 WO disclosed
US-4132596-A Support-aminoacylase complexes RHONE POULENC INDUSTRIES (FR) 1979-01-02 US disclosed