Styrene

Styrene

SCHEMBL9727042

C=Cc1ccccc1.CCO[Si](C)(OCC)OCC

nearest known ligand 0.54

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
TSHR P16473 1/20 0.54
RELA Q04206 1/20 0.39
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
TP53 P04637 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
NR1I2 O75469 1/20 0.35
CHRNA7 P36544 3/20 0.34
CHRNB2 P17787 2/20 0.34
CHRNB4 P30926 2/20 0.34
CHRNA3 P32297 2/20 0.34
CHRNA4 P43681 2/20 0.34
HDAC8 Q9BY41 2/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 2/20 0.33
HPGD P15428 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL28209933 0.86 ALDH1A1 (0.56) ALDH1A1TSHRRELAMEN1KMT2A
Styrene SCHEMBL8746482 0.83 ALDH1A1 (0.52) ALDH1A1TSHRRELAMEN1KMT2A
Styrene SCHEMBL28895192 0.83 ALDH1A1 (0.52) ALDH1A1TSHRRELAMEN1KMT2A
Styrene SCHEMBL27700368 0.83 ALDH1A1 (0.52) ALDH1A1TSHRRELAMEN1KMT2A
Styrene SCHEMBL28104798 0.81 ALDH1A1 (0.50) ALDH1A1TSHRRELAMEN1KMT2A
SCHEMBL16538064 0.80 ALDH1A1 (0.38) ALDH1A1TSHRMEN1KMT2ATP53
Styrene SCHEMBL1732622 0.79 ALDH1A1 (0.64) ALDH1A1TSHRRELAMEN1KMT2A
Styrene SCHEMBL28211071 0.79 ALDH1A1 (0.78) ALDH1A1TSHRRELAMEN1KMT2A
SCHEMBL16537466 0.79 TP53 (0.40) ALDH1A1TSHRTP53TDP1KDM4E
SCHEMBL16537396 0.78 CHRNB2 (0.42) ALDH1A1TSHRRELACHRNA7CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5114820-A Polyalkyl styrene butadiene toner compositions XEROX CORPORATION (US) 1992-05-19 US claimed
US-4954408-A Polysiloxane crosslinked styrene/butadiene copolymers XEROX CORPORATION (US) 1990-09-04 US claimed
US-4770968-A INCORPORATED RELEASE AGENT XEROX CORPORATION (US) 1988-09-13 US claimed