Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7779915 | 0.91 | ELANE (0.46) | ELANEKMT2AMEN1CYP2C19TSHR | |
| SCHEMBL7778739 | 0.90 | ELANE (0.48) | ELANEKMT2AMEN1SMN1; SMN2NPSR1 | |
| SCHEMBL8396368 | 0.89 | ELANE (0.37) | ELANEFAAH | |
| SCHEMBL7779935 | 0.88 | FAAH (0.45) | ELANEFAAHPOLB | |
| SCHEMBL7777587 | 0.88 | ELANE (0.47) | ELANETSHRFAAH | |
| SCHEMBL7778734 | 0.87 | ELANE (0.47) | ELANEKMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL8393391 | 0.85 | ADORA2B (0.35) | ELANETSHRPOLB | |
| SCHEMBL7776777 | 0.85 | ELANE (0.45) | ELANEKMT2AMEN1SMN1; SMN2NPSR1 | |
| SCHEMBL7779003 | 0.85 | ELANE (0.41) | ELANEKMT2ASMN1; SMN2 | |
| SCHEMBL7776769 | 0.84 | ELANE (0.47) | ELANEKMT2AMEN1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809627-B1 | NOVEL BORNEOL DERIVATIVES, METHODS OF MANUFACTURING THEM, AND THEIR PHARMACEUTICAL USE | SCHERING AG (DE) | 2001-09-12 | — | — | EP | disclosed |
| US-6025507-A | Borneol derivatives, methods of manufacturing them, and their pharmaceutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-02-15 | — | — | US | disclosed |
| WO-1996025392-A1 | NOVEL BORNEOL DERIVATIVES, METHODS OF MANUFACTURING THEM, AND THEIR PHARMACEUTICAL USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | disclosed |