Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003997 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2KMT2AMEN1ALDH1A1KEAP1 | |
| SCHEMBL6774900 | 0.78 | POLB (0.43) | SMN1; SMN2KMT2AMEN1ALDH1A1KEAP1 | |
| SCHEMBL8746549 | 0.76 | KMT2A (0.37) | SMN1; SMN2KMT2AMEN1ALDH1A1KEAP1 | |
| SCHEMBL4047990 | 0.74 | CYP19A1 (0.43) | SMN1; SMN2KMT2AMEN1ALDH1A1KEAP1 | |
| SCHEMBL6646866 | 0.74 | KMT2A (0.53) | SMN1; SMN2KMT2AMEN1ALDH1A1KEAP1 | |
| SCHEMBL1810392 | 0.73 | ESR1 (0.59) | SMN1; SMN2KMT2AMEN1ALDH1A1KEAP1 | |
| SCHEMBL4431002 | 0.72 | CYP3A4 (0.34) | SMN1; SMN2KMT2AMEN1ALDH1A1KEAP1 | |
| SCHEMBL13166718 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AMEN1ALDH1A1KEAP1 | |
| SCHEMBL16994749 | 0.69 | SMN1; SMN2 (0.51) | SMN1; SMN2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL10389402 | 0.69 | MEN1 (0.50) | SMN1; SMN2KMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759511-A1 | Improved self-locking fastener, apparatus and method | NYLOK FASTENER CORPORATION (US) | 1997-02-26 | — | — | EP | claimed |
| US-5356254-A | High temperature self-locking threaded fastener | NYLOK FASTENER CORPORATION (US) | 1994-10-18 | — | — | US | claimed |
| EP-0580546-A2 | High temperature self-locking threaded fasteners and method of manufacture | NYLOK FASTENER CORPORATION (US) | 1994-01-26 | — | — | EP | claimed |
| JP-7004419-A | — | — | None | — | — | JP | disclosed |
| EP-0580546-B1 | High temperature self-locking threaded fasteners and method of manufacture | NYLOK FASTENER CORP (US) | 1997-03-26 | — | — | EP | disclosed |
| JP-H074419-A | HIGH-TEMPERATURE SELF-FASTENING SCREW PART AND ITS MANUFACTURE | NYLOK FASTENER CORP | 1995-01-10 | — | — | JP | disclosed |
| US-5356254-A | High temperature self-locking threaded fastener | NYLOK FASTENER CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0580546-A2 | High temperature self-locking threaded fasteners and method of manufacture | NYLOK FASTENER CORPORATION (US) | 1994-01-26 | — | — | EP | disclosed |
| US-5166237-A | A polyphenylene ether, polyamide mixture for paint adhesion | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0282730-A1 | Glass fibre-reinforced polyamide moulding compositions with an increased salt and weather resistance | BAYER AG (DE) | 1988-09-21 | — | — | EP | disclosed |