Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003974 | 0.78 | KDM4E (0.42) | KMT2AALDH1A1SMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL8746537 | 0.76 | SMN1; SMN2 (0.39) | KMT2AALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL12572669 | 0.71 | L3MBTL1 (0.47) | KMT2AALDH1A1SMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL8746547 | 0.71 | L3MBTL1 (0.40) | KMT2AALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL13681549 | 0.70 | SMN1; SMN2 (0.43) | ALDH1A1HTTSMN1; SMN2GAAHPGD | |
| SCHEMBL1004853 | 0.70 | HPGD (0.46) | KMT2AALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL6904405 | 0.68 | KDM4E (0.45) | KMT2AALDH1A1SMN1; SMN2MEN1GAA | |
| SCHEMBL12572668 | 0.67 | L3MBTL1 (0.48) | KMT2AALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL2954974 | 0.67 | POLB (0.41) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL1003997 | 0.67 | SMN1; SMN2 (0.41) | KMT2AALDH1A1HTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759511-A1 | Improved self-locking fastener, apparatus and method | NYLOK FASTENER CORPORATION (US) | 1997-02-26 | — | — | EP | claimed |
| US-5356254-A | High temperature self-locking threaded fastener | NYLOK FASTENER CORPORATION (US) | 1994-10-18 | — | — | US | claimed |
| EP-0580546-A2 | High temperature self-locking threaded fasteners and method of manufacture | NYLOK FASTENER CORPORATION (US) | 1994-01-26 | — | — | EP | claimed |
| JP-7004419-A | — | — | None | — | — | JP | disclosed |
| EP-0580546-B1 | High temperature self-locking threaded fasteners and method of manufacture | NYLOK FASTENER CORP (US) | 1997-03-26 | — | — | EP | disclosed |
| JP-H074419-A | HIGH-TEMPERATURE SELF-FASTENING SCREW PART AND ITS MANUFACTURE | NYLOK FASTENER CORP | 1995-01-10 | — | — | JP | disclosed |
| US-5356254-A | High temperature self-locking threaded fastener | NYLOK FASTENER CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0580546-A2 | High temperature self-locking threaded fasteners and method of manufacture | NYLOK FASTENER CORPORATION (US) | 1994-01-26 | — | — | EP | disclosed |