Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447756 | 0.90 | TSHR (0.50) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL11486977 | 0.78 | TSHR (0.61) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL3903209 | 0.78 | TSHR (0.50) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL9175283 | 0.78 | CYP19A1 (0.50) | TSHRMAPK1HIF1ALMNAMEN1 | |
| SCHEMBL83653 | 0.77 | MEN1 (0.59) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL7782036 | 0.75 | CYP19A1 (0.65) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL4472039 | 0.75 | TSHR (0.57) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL5388132 | 0.75 | TSHR (0.57) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL196830 | 0.75 | TSHR (0.57) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| Dicofol SCHEMBL26640 | 0.74 | TSHR (1.00) | TSHRMAPK1HIF1ALMNACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489140-B1 | METHOD FOR PREPARING 1,1-BIS(CHLOROPHENYL) 2,2,2-TRICHLOROETHANOL | ATOCHEM ELF SA (FR) | 1995-08-02 | — | — | EP | claimed |
| US-5245091-A | PROCESS FOR THE PREPARATION OF 1,1-BIS(CHLOROPHENYL)-2,2,2-TRICHLOROETHANOL | ELF ATOCHEM S.A. (FR) | 1993-09-14 | — | — | US | claimed |
| EP-0489140-A1 | METHOD FOR PREPARING 1,1-BIS(CHLOROPHENYL) 2,2,2-TRICHLOROETHANOL. | ATOCHEM ELF SA (FR) | 1992-06-10 | — | — | EP | claimed |
| WO-1992000264-A1 | METHOD FOR PREPARING 1,1-BIS(CHLOROPHENYL) 2,2,2-TRICHLOROETHANOL | ATOCHEM (FR) | 1992-01-09 | — | — | WO | claimed |
| EP-0407086-B1 | Melamine-containing photoresists of improved sensitivity | ROHM & HAAS (US) | 1997-02-26 | — | — | EP | disclosed |
| EP-0489140-B1 | METHOD FOR PREPARING 1,1-BIS(CHLOROPHENYL) 2,2,2-TRICHLOROETHANOL | ATOCHEM ELF SA (FR) | 1995-08-02 | — | — | EP | disclosed |
| EP-0383054-B1 | A process for preparing environmentally safe dicofol and its formulations | AGAN CHEMICAL MANUFACTURERS (IL) | 1995-06-28 | — | — | EP | disclosed |
| EP-0409689-B1 | A process for the purification of 1,1-bis(4-chlorophenyl)-2,2,2-trichloroethanol | ATOCHEM ELF SA (FR) | 1995-03-22 | — | — | EP | disclosed |
| US-5245091-A | PROCESS FOR THE PREPARATION OF 1,1-BIS(CHLOROPHENYL)-2,2,2-TRICHLOROETHANOL | ELF ATOCHEM S.A. (FR) | 1993-09-14 | — | — | US | disclosed |
| US-5243110-A | DEHYDROCHLORINATION OF 1,1-BIS(R-PHENYL)-2,2,2-TRICHLOROETHANES | ELF ATOCHEM S.A. (FR) | 1993-09-07 | — | — | US | disclosed |
| EP-0489140-A1 | METHOD FOR PREPARING 1,1-BIS(CHLOROPHENYL) 2,2,2-TRICHLOROETHANOL. | ATOCHEM ELF SA (FR) | 1992-06-10 | — | — | EP | disclosed |
| US-5118881-A | Recrystllization from acetic acid; free of DDT and O,P-dicofol | AGAN CHEMICAL MANUFACTURERS, LTD. (IL) | 1992-06-02 | — | — | US | disclosed |
| US-5075512-A | Dissolving in polar solvent mixture, then solvent extraction with n-decane; reuse | SOCIEDAD ESPANOLA DE DESARROLLOS QUIMICOS S.A. (ES) | 1991-12-24 | — | — | US | disclosed |
| EP-0460977-A1 | Process for reducing the amount of DDT-related impurities in 1,1-bis (chlorophenyl)-2,2,2-trichloroethanol | ROHM AND HAAS COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| EP-0409689-A2 | A process for the purification of 1,1-bis(4-chlorophenyl)-2,2,2-trichloroethanol | ELF ATOCHEM S.A. (FR) | 1991-01-23 | — | — | EP | disclosed |
| EP-0407086-A2 | Melamine-containing photoresists of improved sensitivity | ROHM AND HAAS COMPANY (US) | 1991-01-09 | — | — | EP | disclosed |
| EP-0383054-A2 | A process for preparing environmentally safe dicofol and its formulations | AGAN CHEMICAL MANUFACTURERS LTD. (IL) | 1990-08-22 | — | — | EP | disclosed |
| EP-0248954-A1 | Process for reducing the amount of DDT-related impurities in 1,1-bis(chlorophenyl)-2,2,2-trichloro-ethanol | ROHM AND HAAS COMPANY (US) | 1987-12-16 | — | — | EP | disclosed |
| US-4705902-A | DDTR-free 1,1-bis(chlorophenyl)-2,2,2-trichloroethanol | ROHM AND HAAS COMPANY (US) | 1987-11-10 | — | — | US | disclosed |
| EP-0120966-A1 | PROCESS FOR PREPARING BENZOPHENONE DERIVATIVES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1984-10-10 | — | — | EP | disclosed |