SCHEMBL196830

SCHEMBL196830

Clc1ccc(C(Cl)(Cl)Cl)cc1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.57
MAPK1 P28482 3/20 0.57
HIF1A Q16665 2/20 0.57
LMNA P02545 2/20 0.53
CYP2A6 P11509 1/20 0.53
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
CYP19A1 P11511 7/20 0.46
TDP1 Q9NUW8 2/20 0.43
TP53 P04637 1/20 0.43
HPGD P15428 1/20 0.43
CYP3A4 P08684 1/20 0.42
MIF P14174 1/20 0.41
IDO1 P14902 1/20 0.40
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9577502 0.89 TSHR (0.74) TSHRMAPK1HIF1ALMNACYP2A6
SCHEMBL545084 0.86 TSHR (0.67) TSHRMAPK1HIF1ALMNAMEN1
SCHEMBL9816151 0.86 TSHR (0.67) TSHRMAPK1HIF1ALMNAMEN1
SCHEMBL13191313 0.84 CYP19A1 (0.52) TSHRMAPK1HIF1ALMNACYP2A6
SCHEMBL11778847 0.81 CYP19A1 (0.49) TSHRMAPK1HIF1AMEN1KMT2A
SCHEMBL5388132 0.80 TSHR (0.57) TSHRMAPK1HIF1ALMNACYP2A6
SCHEMBL4472039 0.80 TSHR (0.57) TSHRMAPK1HIF1ALMNACYP2A6
SCHEMBL7782036 0.80 CYP19A1 (0.65) TSHRMAPK1HIF1ALMNACYP2A6
SCHEMBL7928488 0.79 TSHR (0.50) TSHRMAPK1HIF1ALMNACYP2A6
SCHEMBL5401000 0.78 LMNA (0.50) TSHRMAPK1HIF1ALMNACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 396 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743438-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2026-05-20 EP claimed
EP-4665705-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2025-12-24 EP claimed
WO-2025068995-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2025-04-03 WO claimed
WO-2024171098-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2024-08-22 WO claimed
CN-115999481-B Continuous production method of p-chlorobenzoyl chloride 山东道可化学有限公司 2023-07-18 CN claimed
CN-114702380-A Method for co-producing p-chlorobenzoyl chloride and caproyl chloride and acyl chloride products thereof 河南特格纳特科技有限公司 2022-07-05 CN claimed
CN-105870514-B A kind of battery liquid and its accumulator 盐城工学院 2018-05-18 CN claimed
CN-106785081-A A kind of battery liquid and its battery 叶晓东 2017-05-31 CN claimed
CN-106450499-A Lead-acid storage battery electrolyte and preparation method thereof 陈申申 2017-02-22 CN claimed
CN-105870514-A Storage battery electrolyte and storage battery thereof 盐城工学院 2016-08-17 CN claimed
US-4334111-A PYROLYSIS OF PHENYL TRIHALOACETATE THE DOW CHEMICAL COMPANY (US) 1982-06-08 US claimed
EP-0009205-B1 PROCESS FOR THE PREPARATION OF AN OPTIONALLY SUBSTITUTED BENZOYL CHLORIDE BAYER AG (DE) 1981-12-30 EP claimed
EP-0024516-A1 4-Fluoro-3-bromobenzoyl fluoride, process for its preparation and for the preparation of 4-fluoro-3-bromobenzoic acid therefrom BAYER AG (DE) 1981-03-11 EP claimed
EP-0009205-A1 Process for the preparation of an optionally substituted benzoyl chloride BAYER AG (DE) 1980-04-02 EP claimed
US-4191711-A Process for the preparation of certain nuclear chlorinated benzotrichlorides BAYER AKTIENGESELLSCHAFT (DE) 1980-03-04 US claimed
US-4163753-A FROM AN ALIPHATIC ACID ANHYDRIDE AND A TRICHLOROMETHYL AROMATIC COMPOUND Diaz Chemical Corporation (US) 1979-08-07 US claimed
US-4098832-A FLUORINATION PROCESS CATALYSED BY MOLYBDENUM PENTACHLORIDE HOOKER CHEMICALS & PLASTICS CORP. (US) 1978-07-04 US claimed
US-4080378-A REACTING A CARBOXYLIC ACID ESTER WITH A TRICHLOROMETHYL SUBSTITUTED AROMATIC COMPOUND IN THE PRESENCE OF A MOLYBDENUM CATALYST DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1978-03-21 US claimed
US-4045502-A FLUORINATION OLIN CORPORATION (US) 1977-08-30 US claimed
US-4013817-A HALOGENATED AROMATIC HYDROCARBON BRIDGESTONE TIRE COMPANY LIMITED (JA) 1977-03-22 US claimed