Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.59 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.45 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29717321 | 0.91 | CHRNA7 (0.48) | CHRNA7TBXAS1L3MBTL1TDP1 | |
| SCHEMBL11150544 | 0.91 | CHRNA7 (0.48) | CHRNA7TBXAS1L3MBTL1TDP1 | |
| SCHEMBL2954088 | 0.87 | CHRNA7 (0.63) | CHRNA7TBXAS1L3MBTL1TDP1FKBP1A | |
| SCHEMBL774736 | 0.84 | KMT2A (0.50) | TBXAS1TDP1 | |
| SCHEMBL148938 | 0.83 | LMNA (0.60) | TDP1 | |
| SCHEMBL1921399 | 0.82 | TSHR (0.49) | CHRNA7TDP1HRH1 | |
| Lithium SCHEMBL30708617 | 0.82 | LMNA (0.58) | TDP1 | |
| SCHEMBL8653753 | 0.82 | CHRNA7 (0.61) | CHRNA7TBXAS1L3MBTL1TDP1FKBP1A | |
| SCHEMBL8194733 | 0.82 | CHRNA7 (0.57) | CHRNA7TBXAS1L3MBTL1TDP1FKBP1A | |
| SCHEMBL27609100 | 0.82 | TDP1 (0.46) | CHRNA7L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503780-B1 | Polymerizable metal-azo and metal-azomethine dyes | MINNESOTA MINING & MFG (US) | 1997-01-08 | — | — | EP | disclosed |
| EP-0508573-B1 | Transfer imaging using metal-azo and metal-azomethine dyes | MINNESOTA MINING & MFG (US) | 1995-06-07 | — | — | EP | disclosed |
| EP-0432995-B1 | Crosslinked pyridinio-acrylate-polymers | SMITH KLINE FRENCH LAB (GB) | 1995-02-22 | — | — | EP | disclosed |
| US-5180705-A | Monoazo or methine metallized dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-01-19 | — | — | US | disclosed |
| US-5166326-A | POLYMERIZABLE METAL-AZO AND METAL-AZOMETHINE DYES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-11-24 | — | — | US | disclosed |
| EP-0508573-A1 | Transfer imaging using metal-azo and metal-azomethine dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-10-14 | — | — | EP | disclosed |
| EP-0503780-A1 | Polymerizable metal-azo and metal-azomethine dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-09-16 | — | — | EP | disclosed |
| US-5098701-A | Copolymers for treatment of coronary heart disease | SMITHKLINE & FRENCH LABORATORIES, LTD. (GB) | 1992-03-24 | — | — | US | disclosed |
| EP-0432995-A1 | Crosslinked pyridinio-acrylate-polymers | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-06-19 | — | — | EP | disclosed |