SCHEMBL1921399

SCHEMBL1921399

C=C(C)C(=O)OCCCc1ccncc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.49
POLB P06746 1/20 0.48
APEX1 P27695 1/20 0.48
HTT P42858 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
THRB P10828 2/20 0.46
LMNA P02545 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP19A1 P11511 1/20 0.41
HRH1 P35367 2/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
THRA P10827 1/20 0.39
RECQL P46063 1/20 0.39
CHRNA7 P36544 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
NAMPT P43490 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1921990 0.94 TSHR (0.54) TSHRPOLBAPEX1HTTTDP1
SCHEMBL7467173 0.90 THRB (0.49) TSHRPOLBAPEX1HTTTDP1
SCHEMBL8733212 0.90 TSHR (0.55) TSHRPOLBAPEX1HTTTDP1
SCHEMBL148938 0.85 LMNA (0.60) TSHRPOLBAPEX1HTTTDP1
Lithium SCHEMBL30708617 0.84 LMNA (0.58) TSHRPOLBAPEX1HTTTDP1
SCHEMBL28694550 0.84 TSHR (0.49) TSHRPOLBAPEX1HTTTDP1
SCHEMBL27637385 0.84 TSHR (0.57) TSHRPOLBAPEX1HTTTDP1
SCHEMBL14944773 0.83 TSHR (0.55) TSHRPOLBAPEX1HTTTDP1
SCHEMBL15814717 0.83 TSHR (0.47) TSHRPOLBAPEX1HTTTDP1
SCHEMBL14321912 0.82 TSHR (0.59) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020198630-A2 WATER COMPATIBLE CATIONIC GRAFT COPOLYMERS AND INK COMPOSITIONS COMPRISING SAME PENN COLOR, INC. (US) 2020-10-01 WO claimed
US-20200308331-A1 WATER COMPATIBLE CATIONIC GRAFT COPOLYMERS AND INK COMPOSITIONS COMPRISING SAME PENN COLOR, INC. 2020-10-01 US claimed
US-20220340703-A1 HYBRIDIZED GRAFT COPOLYMERS IN COATING AND INK COMPOSITIONS PENN COLOR, INC. (US) 2022-10-27 US disclosed
EP-4034581-A1 HYBRIDIZED GRAFT COPOLYMERS IN COATING AND INK COMPOSITIONS Penn Color, Inc. (US) 2022-08-03 EP disclosed
WO-2021062159-A1 HYBRIDIZED GRAFT COPOLYMERS IN COATING AND INK COMPOSITIONS PENN COLOR, INC. (US) 2021-04-01 WO disclosed
US-20200308331-A1 WATER COMPATIBLE CATIONIC GRAFT COPOLYMERS AND INK COMPOSITIONS COMPRISING SAME PENN COLOR, INC. 2020-10-01 US disclosed
WO-2020198630-A2 WATER COMPATIBLE CATIONIC GRAFT COPOLYMERS AND INK COMPOSITIONS COMPRISING SAME PENN COLOR, INC. (US) 2020-10-01 WO disclosed
US-10647804-B2 Methods for making water based cationic polymers for ink, coating, and film applications PENN COLOR, INC. (US) 2020-05-12 US disclosed
EP-3434704-A1 CATIONIC WATER BASED POLYMERS FOR INKJET INKS Penn Color, Inc. (US) 2019-01-30 EP disclosed
US-20160340459-A1 METHODS FOR MAKING WATER BASED CATIONIC POLYMERS FOR INK, COATING, AND FILM APPLICATIONS PENN COLOR, INC. 2016-11-24 US disclosed
US-9441123-B2 Cationic water based polymers for ink, coating, and film applications PENN COLOR, INC. (US) 2016-09-13 US disclosed
EP-2330138-A1 POLYMERIZABLE MONOMER, GRAFT COPOLYMER, AND SURFACE MODIFIER Tokyo University Of Science Educational Foundation Administrative Organization (JP) 2011-06-08 EP disclosed
CN-1032478-C Pigmented coating composition, method for the production thereof and use thereof ROHM & HAAS (US) 1996-08-07 CN disclosed
EP-0407085-B1 Cationic latex paint compositions ROHM & HAAS (US) 1994-02-16 EP disclosed
EP-0322188-B1 AQUEOUS COATING COMPOSITIONS ROHM AND HAAS COMPANY (US) 1992-10-07 EP disclosed
EP-0407085-A2 Cationic latex paint compositions ROHM AND HAAS COMPANY (US) 1991-01-09 EP disclosed
EP-0322188-A1 Aqueous coating compositions ROHM AND HAAS COMPANY (US) 1989-06-28 EP disclosed
US-4406737-A Creping paper using cationic water soluble addition polymer ROHM AND HAAS COMPANY (US) 1983-09-27 US disclosed
US-4318956-A WOVEN OR KNIT FABIRCS ROHM AND HAAS COMPANY (US) 1982-03-09 US disclosed
US-4308092-A POLYMER IN AQUEOUS SOLUTION ROHM AND HAAS COMPANY (US) 1981-12-29 US disclosed