Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746641 | 1.00 | NFE2L2 (0.45) | NFE2L2RELAFGF23SMN1; SMN2HPGD | |
| SCHEMBL873003 | 0.94 | NFE2L2 (0.49) | NFE2L2RELAFGF23SMN1; SMN2HPGD | |
| SCHEMBL2285299 | 0.94 | NFE2L2 (0.49) | NFE2L2RELAFGF23SMN1; SMN2HPGD | |
| SCHEMBL27904806 | 0.91 | APP (0.43) | NFE2L2RELACYP1A2MAPTCYP2C19 | |
| SCHEMBL1464416 | 0.87 | NFE2L2 (0.54) | NFE2L2RELAFGF23SMN1; SMN2NPC1 | |
| SCHEMBL7165245 | 0.87 | APP (0.47) | NFE2L2RELACYP1A2MAPTCYP2C19 | |
| SCHEMBL11574959 | 0.85 | NFE2L2 (0.56) | NFE2L2RELAFGF23HPGDMAPT | |
| SCHEMBL8746645 | 0.85 | PELI1 (0.44) | NFE2L2RELAFGF23SMN1; SMN2HPGD | |
| SCHEMBL10426423 | 0.85 | RELA (0.40) | NFE2L2RELAFGF23SMN1; SMN2HPGD | |
| SCHEMBL15988071 | 0.84 | APP (0.47) | NFE2L2RELACYP1A2MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506387-B1 | Electrophotographic organic photosensitive material | MITA INDUSTRIAL CO LTD (JP) | 1997-02-26 | — | — | EP | disclosed |
| US-5324610-A | Improved sensitivity, residual potential | MITA INDUSTRIAL CO., LTD. (JP) | 1994-06-28 | — | — | US | disclosed |
| EP-0506387-A2 | Electrophotographic organic photosensitive material | MITA INDUSTRIAL CO., LTD. (JP) | 1992-09-30 | — | — | EP | disclosed |