Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
| ▸ | CA4 | P22748 | 1/20 | 0.67 |
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | CTSL | P07711 | 4/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | JUN | P05412 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | IAPP | P10997 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746630 | 0.90 | PARP1 (0.69) | NFKB1CA1CA2CA4PARP1 | |
| SCHEMBL11138672 | 0.90 | PARP1 (0.69) | NFKB1CA1CA2CA4PARP1 | |
| SCHEMBL16048249 | 0.89 | CTSL (0.64) | NFKB1CA1CA2CA4PARP1 | |
| SCHEMBL16048251 | 0.89 | CTSL (0.64) | NFKB1CA1CA2CA4PARP1 | |
| SCHEMBL8726893 | 0.82 | NFKB1 (0.61) | NFKB1CA1CA2CA4PARP1 | |
| SCHEMBL6852509 | 0.82 | NFKB1 (0.61) | NFKB1CA1CA2CA4PARP1 | |
| SCHEMBL3423096 | 0.82 | CA1 (0.53) | NFKB1CA1CA2CA4PARP1 | |
| SCHEMBL8746629 | 0.82 | CA1 (0.53) | NFKB1CA1CA2CA4PARP1 | |
| SCHEMBL307296 | 0.81 | NFKB1 (0.71) | NFKB1CA1CA2CA4PARP1 | |
| SCHEMBL31256670 | 0.81 | NFKB1 (0.71) | NFKB1CA1CA2CA4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644232-B1 | Free radical cured rubber | GOODYEAR TIRE & RUBBER (US) | 1997-03-05 | — | — | EP | disclosed |
| EP-0644232-A1 | Free radical cured rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-03-22 | — | — | EP | disclosed |
| US-5310811-A | Abrasion resistance | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-05-10 | — | — | US | disclosed |