SCHEMBL8416364

SCHEMBL8416364

C/C(=C\c1ccccc1C=O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.59
MEN1 O00255 1/20 0.52
LMNA P02545 1/20 0.52
THRB P10828 1/20 0.52
BLM P54132 1/20 0.52
KMT2A Q03164 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
APEX1 P27695 8/20 0.45
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
TRIM24 O15164 1/20 0.43
TRIM33 Q9UPN9 1/20 0.43
ERN1 O75460 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.41
HTT P42858 1/20 0.41
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
NR4A2 P43354 1/20 0.41
RXRG P48443 1/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7525200 1.00 AKR1C3 (0.59) AKR1C3MEN1LMNATHRBBLM
SCHEMBL31666241 0.92 AKR1C3 (0.68) AKR1C3LMNAAPEX1HTTRXRA
SCHEMBL3893886 0.92 AKR1C3 (0.68) AKR1C3LMNAAPEX1HTTRXRA
SCHEMBL8746671 0.92 AKR1C3 (0.68) AKR1C3LMNAAPEX1HTTRXRA
Ortho-Phthalaldehyde SCHEMBL11471020 0.83 LMNA (0.68) AKR1C3MEN1LMNATHRBBLM
Ortho-Phthalaldehyde SCHEMBL21141617 0.83 LMNA (0.68) AKR1C3MEN1LMNATHRBBLM
SCHEMBL14040079 0.82 AKR1C3 (0.57) AKR1C3APEX1ALDH1A1HTTRXRA
SCHEMBL28588058 0.82 AKR1C3 (0.57) AKR1C3APEX1ALDH1A1HTTRXRA
SCHEMBL7764991 0.82 AKR1C3 (0.61) AKR1C3APEX1HTTRXRARXRB
SCHEMBL7764986 0.82 AKR1C3 (0.61) AKR1C3APEX1HTTRXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0833870-B1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF JOTUN AS (NO) 1999-09-08 EP claimed
EP-0841380-B1 Method of making polymeric binders and use thereof in antifouling paints WITCO GMBH (DE) 1999-08-25 EP claimed
EP-0841380-A1 Method of making polymeric binders and use thereof in antifouling paints Witco GmbH (DE) 1998-05-13 EP claimed
EP-0841380-B1 Method of making polymeric binders and use thereof in antifouling paints WITCO GMBH (DE) 1999-08-25 EP disclosed
US-5891935-A Process for preparing polymeric binders and their use for antifouling paint systems WITCO GMBH (DE) 1999-04-06 US disclosed
EP-0841380-A1 Method of making polymeric binders and use thereof in antifouling paints Witco GmbH (DE) 1998-05-13 EP disclosed