Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746758 | 1.00 | BTK (0.44) | BTKCNR1CNR2IRAK4GPR119 | |
| SCHEMBL8746780 | 0.89 | BTK (0.46) | BTKIRAK4 | |
| SCHEMBL8746781 | 0.89 | BTK (0.46) | BTKIRAK4 | |
| SCHEMBL8488267 | 0.86 | KMT2A (0.41) | BTKCNR1CNR2 | |
| SCHEMBL8488266 | 0.86 | KMT2A (0.41) | BTKCNR1CNR2 | |
| SCHEMBL8754064 | 0.84 | BTK (0.38) | BTKIRAK4 | |
| SCHEMBL8754074 | 0.84 | BTK (0.38) | BTKIRAK4 | |
| SCHEMBL8746770 | 0.83 | BTK (0.47) | BTKIRAK4 | |
| SCHEMBL8746756 | 0.83 | BTK (0.41) | BTKIRAK4 | |
| SCHEMBL8914933 | 0.83 | BTK (0.47) | BTKIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691321-A | INSECTICIDES, MITICIDES, PARASITICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1997-11-25 | — | — | US | disclosed |
| EP-0759909-A1 | HETEROCYCLYLAMINO- AND HETEROCYCLYLOXY-CYCLOALKYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031441-A1 | HETEROCYCLYLAMINO- AND HETEROCYCLYLOXY-CYCLOALKYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-11-23 | — | — | WO | disclosed |