Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2990923 | 0.90 | TDP1 (0.55) | TDP1CES1CA1CA2SRD5A2 | |
| SCHEMBL14638882 | 0.80 | MAPK1 (0.50) | TDP1CES1CA1CA2SRD5A2 | |
| SCHEMBL10585970 | 0.77 | CES1 (0.57) | TDP1CES1CA1CA2SRD5A2 | |
| SCHEMBL21273296 | 0.77 | KMT2A (0.50) | TDP1CES1CA1CA2MAPK1 | |
| SCHEMBL10784508 | 0.75 | CES1 (0.62) | TDP1CES1CA1CA2SRD5A2 | |
| SCHEMBL4944977 | 0.75 | TDP1 (0.69) | TDP1CES1CA1CA2SRD5A2 | |
| SCHEMBL2099160 | 0.75 | CES1 (0.79) | TDP1CES1CA1CA2SRD5A2 | |
| SCHEMBL4949082 | 0.75 | TDP1 (0.69) | TDP1CES1CA1CA2SRD5A2 | |
| SCHEMBL15180824 | 0.75 | CES1 (0.79) | TDP1CES1CA1CA2SRD5A2 | |
| 4-Nitrobenzoic Acid SCHEMBL43476 | 0.74 | TDP1 (1.00) | TDP1CES1CA1CA2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4038253-A | PHOTOCROSS-LINKABLE POLYMERS CONTAINING PENDANT DIAZOESTER GROUPS | HERCULES INCORPORATED (US) | 1977-07-26 | — | — | US | claimed |
| EP-0752426-A2 | Synthetic calibrators for use in immunoassays, consisting of analytes or parts thereof conjugated to inert carrier molecules | BAYER AG (DE) | 1997-01-08 | — | — | EP | disclosed |
| US-4038253-A | PHOTOCROSS-LINKABLE POLYMERS CONTAINING PENDANT DIAZOESTER GROUPS | HERCULES INCORPORATED (US) | 1977-07-26 | — | — | US | disclosed |