Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14638882 | 0.84 | MAPK1 (0.50) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL7699081 | 0.83 | CES1 (0.50) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL34462714 | 0.83 | MAPK1 (0.44) | KMT2AALDH1A1MAPTMEN1MAPK1 | |
| SCHEMBL478613 | 0.80 | CES1 (0.61) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL29001221 | 0.80 | CA1 (0.56) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL17338792 | 0.79 | KMT2A (0.50) | KMT2AALDH1A1MAPTMEN1LMNA | |
| SCHEMBL28399426 | 0.79 | MAPT (0.50) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL28393255 | 0.79 | KYAT1 (0.39) | KMT2AALDH1A1MAPTMEN1LMNA | |
| SCHEMBL28783011 | 0.79 | SMN1; SMN2 (0.49) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL900466 | 0.79 | ALDH1A1 (0.54) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116368-B | Green preparation method of aryl alpha-keto acid ester compound | 河南师范大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-114736124-A | Method for constructing quaternary carbon center by selectively inserting iron-catalyzed diazo compound into C (sp) -C (sp3) bond of propargyl alcohol | 湖南警察学院 | 2022-07-12 | — | — | CN | disclosed |
| US-11279677-B2 | Photochromic hydrazone switches | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2022-03-22 | — | — | US | disclosed |
| CN-111116368-A | Green preparation method of aryl α -keto acid ester compound | 河南师范大学 | 2020-05-08 | — | — | CN | disclosed |
| EP-3535348-A1 | PHOTOCHROMIC HYDRAZONE SWITCHES | Trustees of Dartmouth College (US) | 2019-09-11 | — | — | EP | disclosed |
| US-20190256472-A1 | PHOTOCHROMIC HYDRAZONE SWITCHES | DARTMOUTH COLLEGE (US) | 2019-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256472-A1 | PHOTOCHROMIC HYDRAZONE SWITCHES | CRYZ, PIN1, PPOX | KMT2A 792/4885ALDH1A1 404/4885MAPT 702/4885 |
| US-11279677-B2 | Photochromic hydrazone switches | CRYZ, PIN1, PPOX | KMT2A 792/4885ALDH1A1 404/4885MAPT 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.