Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17213617 | 0.89 | GAA (0.66) | GAAHTTUSP2RECQLPOLB | |
| SCHEMBL10812553 | 0.82 | GAA (0.70) | GAAHTTUSP2RECQLPOLB | |
| SCHEMBL15749724 | 0.81 | GAA (0.65) | GAAHTTUSP2RECQLPOLB | |
| SCHEMBL15749705 | 0.79 | GAA (0.62) | GAAHTTUSP2RECQLPOLB | |
| SCHEMBL15750029 | 0.79 | GAA (0.66) | GAAHTTUSP2RECQLPOLB | |
| SCHEMBL26447496 | 0.77 | ALDH1A1 (0.72) | GAAPOLBMAPTALOX15ADORA2A | |
| SCHEMBL19969306 | 0.77 | ALDH1A1 (0.72) | GAAPOLBMAPTALOX15ADORA2A | |
| SCHEMBL24559426 | 0.77 | POLB (1.00) | GAAHTTUSP2RECQLPOLB | |
| SCHEMBL24559315 | 0.76 | POLB (0.68) | GAAHTTUSP2RECQLPOLB | |
| SCHEMBL10652432 | 0.76 | ALDH1A1 (0.74) | GAAPOLBMAPTALOX15ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485156-B1 | Methods and compounds for labeling DNA with xanthine and lower alkyl substituted xanthine derivatives and reagents for the in situ detection of chromosomes | AMOCO CORP (US) | 1997-03-05 | — | — | EP | disclosed |
| US-5512433-A | XANTHINE OR ALKYL SUBSTITUTED XANTHINE DERIVATIVE LABELS ARE CONVALENTLY LINKED TO DNA SEQUENCES, XANTHINE LINKED DNA REAGENTS ARE HYBRIDIZED WITH CHROMOSOME OR SPECIFIC REGIONS OF CHROMOSOME, BINDING IS DETECTED BY IMMUNOLOGICAL TECHNIQUE | VYSIS, INC. (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0612357-A1 | METHODS FOR DETECTION OF CHROMOSOMAL STURCTURE AND REARRANGEMENTS | AMOCO CORPORATION (US) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993017128-A1 | METHODS FOR DETECTION OF CHROMOSOMAL STURCTURE AND REARRANGEMENTS | AMOCO CORPORATION (US) | 1993-09-02 | — | — | WO | disclosed |
| EP-0485156-A1 | Methods and compounds for labeling DNA with xanthine and lower alkyl substituted xanthine derivatives and reagents for the in situ detection of chromosomes | AMOCO CORPORATION (US) | 1992-05-13 | — | — | EP | disclosed |