Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.60 |
| ▸ | DRD1 | P21728 | 4/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8747231 | 0.96 | DRD2 (0.56) | DRD2DRD1CYP2D6KCNH2MAOA | |
| SCHEMBL8747234 | 0.87 | CYP2D6 (0.46) | DRD2DRD1CYP2D6KCNH2PDE4B | |
| SCHEMBL8747012 | 0.86 | DRD1 (0.50) | DRD2DRD1MAOA | |
| SCHEMBL8747191 | 0.85 | DRD1 (0.56) | DRD2DRD1KCNH2MAOA | |
| SCHEMBL8747029 | 0.84 | DRD1 (0.50) | DRD2DRD1MAOA | |
| SCHEMBL8747267 | 0.83 | CHRNA7 (0.46) | DRD2DRD1CYP2D6 | |
| SCHEMBL8747299 | 0.83 | DRD1 (0.47) | DRD2DRD1KCNH2MAOA | |
| SCHEMBL8747074 | 0.83 | DRD1 (0.49) | DRD2DRD1MAOA | |
| SCHEMBL8747084 | 0.83 | MAOA (0.45) | DRD2DRD1KCNH2MAOA | |
| Hydrochloric Acid SCHEMBL8747265 | 0.83 | CHRNA7 (0.46) | DRD2DRD1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618900-B1 | SUBSTITUTED TETRAHYDROISOQUINOLINES AND THEIR USE AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1997-03-12 | — | — | EP | disclosed |
| US-5519034-A | ANALGESICS | THE BOOTS COMPANY PLC (GB) | 1996-05-21 | — | — | US | disclosed |