SCHEMBL8747189

SCHEMBL8747189

O=C(c1ccc(C(=O)N2CC2)cc1)N1CC1

nearest known ligand 0.76

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.76
ALDH1A1 P00352 5/20 0.76
PKM P14618 1/20 0.64
POLB P06746 2/20 0.63
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
LMNA P02545 1/20 0.61
HTT P42858 1/20 0.61
MAPK1 P28482 1/20 0.59
ALOX15 P16050 1/20 0.59
L3MBTL3 Q96JM7 2/20 0.57
MLYCD O95822 1/20 0.57
PHGDH O43175 1/20 0.57
USP2 O75604 1/20 0.57
MBTD1 Q05BQ5 1/20 0.57
TP53BP1 Q12888 1/20 0.57
L3MBTL4 Q8NA19 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9133746 0.90 ALDH1A1 (0.64) HPGDALDH1A1PKMPOLBMEN1
SCHEMBL14523155 0.90 HPGD (0.64) HPGDALDH1A1PKMPOLBMEN1
SCHEMBL10721733 0.89 HPGD (0.95) HPGDALDH1A1MEN1KMT2ALMNA
SCHEMBL10724841 0.88 POLB (0.81) HPGDALDH1A1POLBMEN1KMT2A
SCHEMBL10722382 0.88 POLB (0.81) HPGDALDH1A1POLBKMT2ALMNA
SCHEMBL9585721 0.88 POLB (0.81) HPGDALDH1A1POLBKMT2ALMNA
SCHEMBL538998 0.88 ALDH1A1 (0.61) HPGDALDH1A1PKMPOLBMEN1
SCHEMBL20261717 0.88 CA12 (0.73) HPGDALDH1A1PKMPOLBMEN1
SCHEMBL22305103 0.88 CA12 (0.71) HPGDALDH1A1POLBMEN1KMT2A
SCHEMBL6985975 0.88 CA12 (0.71) HPGDALDH1A1POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0535788-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-03-05 EP claimed
EP-0512560-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-20 EP claimed
EP-0526072-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-09-13 EP claimed
EP-0514807-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-08-23 EP claimed
EP-0542556-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP claimed
US-5384303-A Heat sensitive elements for color images with stabilizers NEW OJI PAPER CO., LTD. (JP) 1995-01-24 US claimed
US-5314859-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-05-24 US claimed
US-5312796-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-05-17 US claimed
US-5292711-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-03-08 US claimed
US-5246906-A Sulfonyl-urea or -thiourea color developer, oil and plasticizer resistant, storage stable OJI PAPER CO., LTD. (JP) 1993-09-21 US claimed
EP-0542556-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-05-19 EP claimed
EP-0535788-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-04-07 EP claimed
EP-0526072-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-02-03 EP claimed
EP-0514807-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1992-11-25 EP claimed
EP-0512560-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1992-11-11 EP claimed
EP-0503856-A1 Thermosensitive recording material OJI PAPER COMPANY LIMITED (JP) 1992-09-16 EP claimed
JP-56109223-A None JP disclosed
EP-0610653-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-04-16 EP disclosed
EP-0503856-A1 Thermosensitive recording material OJI PAPER COMPANY LIMITED (JP) 1992-09-16 EP disclosed
JP-S56109223-A MODIFICATION OF POLYESTER TEIJIN LTD 1981-08-29 JP disclosed