SCHEMBL8747296

SCHEMBL8747296

CCCCC(CCCCCCCC(=O)O)(Cc1ccccc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
GPR84 Q9NQS5 7/20 0.44
PPARG P37231 7/20 0.44
PPARD Q03181 7/20 0.44
PPARA Q07869 7/20 0.44
HDAC11 Q96DB2 6/20 0.44
TSHR P16473 4/20 0.44
PTPN1 P18031 3/20 0.44
ALDH1A1 P00352 2/20 0.44
TLR2 O60603 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
FABP4 P15090 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
SLC22A6 Q4U2R8 1/20 0.44
SLC22A8 Q8TCC7 1/20 0.44
ESR1 P03372 1/20 0.44
ALOX15 P16050 1/20 0.44
PDE4A P27815 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11128103 0.94 MAPT (0.45) MAPTRXFP1GPR84PPARGPPARD
SCHEMBL1034999 0.94 MAPT (0.45) MAPTRXFP1GPR84PPARGPPARD
SCHEMBL11128523 0.94 MAPT (0.45) MAPTRXFP1GPR84PPARGPPARD
SCHEMBL1122046 0.94 HDAC11 (0.46) MAPTRXFP1GPR84PPARGPPARD
SCHEMBL29286131 0.91 EPHX2 (0.44) MAPTRXFP1GPR84PPARGPPARD
SCHEMBL3823945 0.91 HPGD (0.42) MAPTRXFP1HDAC11MEN1KMT2A
SCHEMBL27784180 0.90 MAPT (0.50) MAPTRXFP1HDAC11TSHRALDH1A1
SCHEMBL9191113 0.90 MAPT (0.56) MAPTRXFP1HDAC11TSHRALDH1A1
SCHEMBL4477456 0.90 MAPT (0.56) MAPTRXFP1HDAC11TSHRALDH1A1
SCHEMBL31303729 0.90 MAPT (0.56) MAPTRXFP1HDAC11TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0537998-B1 Controlled release drug delivery device comprising a polymer matrix and a plasticizer MERCK & CO INC (US) 1997-01-15 EP claimed
EP-0160726-B1 CONTINUOUS PROCESS FOR PRODUCTION OF BUBBLE GUM NABISCO BRANDS, Inc. (US) 1988-04-20 EP claimed
EP-0066864-B1 NEW CHEWING GUM BASE AND THEIR USE IN A CHEWING GUM NABISCO BRANDS, Inc. (US) 1986-03-05 EP claimed
EP-0118721-B1 PROCESS FOR PREPARING A CONCENTRATE OF CARBON BLACK ON THE BASIS OF NITROCELLULOSE IN THE FORM OF CHIPS Degussa Aktiengesellschaft (DE) 1987-09-02 EP disclosed
US-4615852-A BLENDING SOLVENT-FREE MIXTURE WITH PLASTICIZER AND WETTING AGENT, FORMING DISPERSION KNEADING INTO FILM, AND CRUSHING DEGUSSA AKTIENGESELLSCHAFT (DE) 1986-10-07 US disclosed
EP-0118721-A2 Process for preparing a concentrate of carbon black on the basis of nitrocellulose in the form of chips Degussa Aktiengesellschaft (DE) 1984-09-19 EP disclosed