SCHEMBL1122046

SCHEMBL1122046

CCCCC(CCCC(=O)O)(Cc1ccccc1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC11 Q96DB2 6/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HDAC3 O15379 1/20 0.46
MAPK1 P28482 1/20 0.46
ADRA1A P35348 1/20 0.46
HDAC4 P56524 1/20 0.46
SLC6A3 Q01959 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46
HDAC5 Q9UQL6 1/20 0.46
MAPT P10636 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
HPGD P15428 1/20 0.42
HIF1A Q16665 1/20 0.41
KEAP1 Q14145 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1034999 0.94 MAPT (0.45) HDAC11SMN1; SMN2HDAC3MAPK1ADRA1A
SCHEMBL11128523 0.94 MAPT (0.45) HDAC11SMN1; SMN2HDAC3MAPK1ADRA1A
SCHEMBL11128103 0.94 MAPT (0.45) HDAC11SMN1; SMN2HDAC3MAPK1ADRA1A
SCHEMBL8747296 0.94 MAPT (0.49) HDAC11SMN1; SMN2HDAC3MAPK1ADRA1A
SCHEMBL3823945 0.94 HPGD (0.42) HDAC11SMN1; SMN2HDAC3MAPK1ADRA1A
SCHEMBL27681244 0.89 SMN1; SMN2 (0.47) HDAC11SMN1; SMN2HDAC3MAPK1ADRA1A
SCHEMBL675542 0.89 SMN1; SMN2 (0.53) HDAC11SMN1; SMN2HDAC3MAPK1ADRA1A
SCHEMBL29286131 0.88 EPHX2 (0.44) HDAC11MAPTRXFP1HPGDEPHX2
SCHEMBL38654259 0.87 ALDH1A1 (0.40) HDAC11SMN1; SMN2HDAC3MAPK1ADRA1A
SCHEMBL27784180 0.84 MAPT (0.50) HDAC11SMN1; SMN2HDAC3MAPK1ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0047215-B1 MIXTURE OF PLASTICIZERS FOR POLYVINYL BUTYRAL RESINS, APPLICATION TO INTERLAYERS FOR LAMINATED SAFETY GLASS SAINT GOBAIN VITRAGE INTERNATIONAL (FR) 1984-08-08 EP claimed
EP-2978805-B1 STABILIZER COMPOSITIONS COMPRISING SALTS OF DICARBOXYLIC ACIDS AND POLYOLS BAERLOCHER GMBH (DE) 2023-11-15 EP disclosed
EP-2978805-A1 STABILIZER COMPOSITIONS COMPRISING SALTS OF DICARBOXYLIC ACIDS AND POLYOLS Baerlocher GmbH (DE) 2016-02-03 EP disclosed
EP-1565518-B2 STABILIZER COMPOSITION FOR FOAMS OF HALOGEN-CONTAINING POLYMERS BAERLOCHER GMBH (DE) 2015-06-17 EP disclosed
WO-2014154520-A1 STABILIZER COMPOSITIONS COMPRISING SALTS OF DICARBOXYLIC ACIDS AND POLYOLS BAERLOCHER GMBH (DE) 2014-10-02 WO disclosed
WO-2011101274-A1 STABILIZER SYSTEM FOR FOAMING POLYMERS CONTAINING HALOGEN IKA INNOVATIVE KUNSTSTOFFAUFBEREITUNG GMBH & CO. KG (DE) 2011-08-25 WO disclosed
EP-1694768-B2 STABILIZER COMPOSITION FOR HALOGENATED POLYMERS BAERLOCHER GMBH (DE) 2011-08-03 EP disclosed
EP-1913070-B1 STABILISER COMPOSITIONS BASED ON NITROGEN COMPOUNDS FOR STABILISING HALOGENATED POLYMERS BAERLOCHER GMBH (DE) 2011-07-06 EP disclosed
EP-1836251-B1 STABILIZER COMPOSITION CONTAINING PHOSPHITE ESTERS BAERLOCHER ITALIA S P A (IT) 2011-02-09 EP disclosed
EP-1912892-B1 SOLID SALT PREPARATION, THE PRODUCTION THEREOF AND ITS USE BAERLOCHER GMBH (DE) 2010-09-22 EP disclosed
EP-0465403-A1 Pressure sensitive recording and transfer material CIBA-GEIGY AG (CH) 1992-01-08 EP disclosed
EP-0463987-A1 Pressure sensitive recording material CIBA-GEIGY AG (CH) 1992-01-02 EP disclosed
EP-0453395-A1 Pressure sensitive recording material CIBA-GEIGY AG (CH) 1991-10-23 EP disclosed
EP-0433230-A1 Beta-ketoesters as stabilizers for chlorine containing polymerisates CIBA-GEIGY AG (CH) 1991-06-19 EP disclosed
EP-0432096-A1 Stabilised chlorine-containing composition CIBA-GEIGY AG (CH) 1991-06-12 EP disclosed
EP-0421933-A1 Stabilized chlorinated polymer compositions CIBA-GEIGY AG (CH) 1991-04-10 EP disclosed
EP-0415885-A1 Bis-Phthalideactones, process for their preparation, and their use in recording materials CIBA-GEIGY AG (CH) 1991-03-06 EP disclosed
EP-0377406-A1 Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY AG (CH) 1990-07-11 EP disclosed
EP-0373110-A2 Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY AG (CH) 1990-06-13 EP disclosed
EP-0035669-A2 Aqueous dispersions and process for making them BAYER AG (DE) 1981-09-16 EP disclosed