Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1108184 | 0.98 | MAOB (0.61) | MAOBALDH1A1HTTTSHRMEN1 | |
| Acetic Acid SCHEMBL1357849 | 0.95 | MAOB (0.58) | MAOBALDH1A1HTTTSHRMEN1 | |
| Acetic Acid SCHEMBL9258637 | 0.85 | MAOB (0.49) | MAOBALDH1A1HTTTSHRMEN1 | |
| SCHEMBL286962 | 0.85 | MAOB (0.56) | MAOBALDH1A1HTTTSHRMEN1 | |
| SCHEMBL5604448 | 0.84 | MAOB (0.50) | MAOBALDH1A1HTTTSHRMEN1 | |
| SCHEMBL11062937 | 0.84 | TDP1 (0.53) | MAOBALDH1A1HTTTSHRMEN1 | |
| SCHEMBL7421292 | 0.84 | MAOB (0.52) | MAOBALDH1A1HTTTSHRMEN1 | |
| SCHEMBL1104649 | 0.84 | MAOB (0.56) | MAOBALDH1A1HTTTSHRMEN1 | |
| SCHEMBL5932809 | 0.83 | MAOB (0.55) | MAOBALDH1A1HTTTSHRMEN1 | |
| SCHEMBL602067 | 0.83 | MAOB (0.55) | MAOBALDH1A1HTTTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548186-B1 | CEPHALOSPORIN DERIVATIVES AND THEIR HOMOLOGUES | BEECHAM GROUP PLC (GB) | 1997-03-05 | — | — | EP | disclosed |
| EP-0416810-B1 | Cephalosporin compounds, process for their preparation, pharmaceutical compositions and intermediates | BEECHAM GROUP PLC (GB) | 1995-02-08 | — | — | EP | disclosed |
| US-5275816-A | Cephalosporin derivatives | BEECHAM GROUP P.L.C. (GB) | 1994-01-04 | — | — | US | disclosed |
| EP-0548186-A1 | CEPHALOSPORIN DERIVATIVES AND THEIR HOMOLOGUES. | BEECHAM GROUP PLC (GB) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992004353-A1 | CEPHALOSPORIN DERIVATIVES AND THEIR HOMOLOGUES | BEECHAM GROUP PLC (GB) | 1992-03-19 | — | — | WO | disclosed |
| EP-0416810-A2 | Cephalosporin compounds, process for their preparation, pharmaceutical compositions and intermediates | Beecham Group p.l.c. (GB) | 1991-03-13 | — | — | EP | disclosed |