Sugi Predict

Sugi Predict / Compounds / SCHEMBL286962

SCHEMBL286962

SCHEMBL286962

O=C(OCc1ccccc1[N+](=O)[O-])OCc1ccccc1[N+](=O)[O-]

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 1/20 0.56
▸ ALDH1A1 P00352 7/20 0.55
▸ TSHR P16473 1/20 0.55
▸ HTT P42858 1/20 0.54
▸ HPGD P15428 1/20 0.50
▸ L3MBTL1 Q9Y468 1/20 0.49
▸ NPC1 O15118 3/20 0.47
▸ RAB9A P51151 3/20 0.47
▸ MEN1 O00255 3/20 0.47
▸ KMT2A Q03164 3/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ CYP2D6 P10635 1/20 0.47
▸ CYP2C19 P33261 1/20 0.47
▸ CTSD P07339 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4441189 0.92 MAOB (0.52) MAOBALDH1A1TSHRHTTHPGD
SCHEMBL27687104 0.90 ALDH1A1 (0.53) MAOBALDH1A1TSHRHTTHPGD
SCHEMBL164758 0.88 MAOB (0.47) MAOBALDH1A1TSHRHTTHPGD
SCHEMBL602068 0.88 MAOB (0.55) MAOBALDH1A1TSHRHTTHPGD
SCHEMBL602067 0.88 MAOB (0.55) MAOBALDH1A1TSHRHTTHPGD
SCHEMBL5932809 0.88 MAOB (0.55) MAOBALDH1A1TSHRHTTHPGD
SCHEMBL10907707 0.88 ALDH1A1 (0.50) MAOBALDH1A1TSHRHTTHPGD
SCHEMBL3122029 0.88 MAOB (0.52) MAOBALDH1A1TSHRHTTHPGD
SCHEMBL4444551 0.88 MAOB (0.49) MAOBALDH1A1TSHRHTTHPGD
SCHEMBL258506 0.86 ALDH1A1 (0.56) MAOBALDH1A1TSHRHTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1988 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035402-A1 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF ZIKANI THERAPEUTICS INC (US) 2026-02-05 — — US claimed
CN-119350283-A Prazomycin impurity H and preparation method thereof 上海上药新亚药业有限公司 2025-01-24 — — CN claimed
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-08-13 — — US claimed
EP-4343326-A1 BIOLOGICAL CONJUGATES HAVING AN PHOTOGENERATED ACIDIC OR BASIC RELEASABLE DETECTION MOIETY ON TOP OF BIOLOGICAL TISSUES Miltenyi Biotec B.V. & Co. KG (DE) 2024-03-27 — — EP claimed
US-20240094198-A1 BIOLOGICAL CONJUGATES HAVING AN PHOTOGENERATED ACIDIC OR BASIC RELEASABLE DETECTION MOIETY ON TOP OF BIOLOGICAL TISSUES Miltenyi Biotec B.V. & Co. KG (DE) 2024-03-21 — — US claimed
US-20230373962-A1 SUPRAMOLECULAR MOLECULES FOR THE TREATMENT OF CANCER THE UNIVERSITY OF BIRMINGHAM (GB) 2023-11-23 — — US claimed
EP-3606528-B1 TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF BROAD INST INC (US) 2023-10-18 — — EP claimed
US-11634449-B2 Macrolides and methods of their preparation and use PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-04-25 — — US claimed
EP-3649135-B1 SYNTHESIS OF HALICHONDRINS HARVARD COLLEGE (US) 2022-12-28 — — EP claimed
US-20220332747-A1 MACROLIDES AND METHODS OF THEIR PREPARATION AND USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-10-20 — — US claimed
US-20200256862-A1 FUNCTIONALIZED SOLID SUPPORT MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2020-08-13 — — US claimed
EP-3063164-B1 SYNTHETIC ROUTE TO 2'-DEOXY-2',2'-DIFLUOROTETRAHYDROURIDINES OTSUKA PHARMA CO LTD (JP) 2018-12-05 — — EP claimed
CN-103224474-B The synthesis of tetracycline and the like 哈佛大学校长及研究员协会 2016-08-03 — — CN claimed
CN-105555759-A Compounds with antibacterial activity FUND MEDINA CT DE EXCELENCIA EN INVESTIG DE MEDICAMENTOS INNOVADORES EN ANDALUCIA 2016-05-04 — — CN claimed
EP-2727915-B1 Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof CONCERT PHARMACEUTICALS INC (US) 2016-04-13 — — EP claimed
EP-2727915-A1 Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof Concert Pharmaceuticals Inc. (US) 2014-05-07 — — EP claimed
US-20100021970-A1 Nucleic Acid Amplification Using a Reversibly Modified Oligonucleotide BI WANLI 2010-01-28 — — US claimed
EP-2049689-A2 NUCLEIC ACID AMPLIFICATION USING A REVERSIBLY MODIFIED OLIGONUCLEOTIDE Bi, Wanli (US) 2009-04-22 — — EP claimed
WO-2008016562-A2 NUCLEIC ACID AMPLIFICATION USING A REVERSIBLY MODIFIED OLIGONUCLEOTIDE BI WANLI (US) 2008-02-07 — — WO claimed
WO-2005058246-A2 METHOD FOR PREPARING RADIOLABELED THYMIDINE MOLECULAR TECHNOLOGIES, INC. (US) 2005-06-30 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035402-A1 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF MALT1, CCR10, CYP51A1 MAOB 2225/4885ALDH1A1 1752/4885TSHR 945/4885
US-20230373962-A1 SUPRAMOLECULAR MOLECULES FOR THE TREATMENT OF CANCER PCNA, DDX1, DDX18 MAOB 4583/4885ALDH1A1 4454/4885TSHR 3073/4885
US-20220332747-A1 MACROLIDES AND METHODS OF THEIR PREPARATION AND USE CYP11B2, ERG28, DHCR7 MAOB 969/4885ALDH1A1 1071/4885TSHR 3696/4885
US-11634449-B2 Macrolides and methods of their preparation and use CYP11B2, ERG28, DHCR7 MAOB 969/4885ALDH1A1 1071/4885TSHR 3696/4885
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents ROS1, NOX4, NOX5 MAOB 338/4885ALDH1A1 348/4885TSHR 1680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.