SCHEMBL8747398

SCHEMBL8747398

CCCCCCCCCCCCS(=O)(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 3/20 0.55
ITGA2B P08514 2/20 0.55
SLC6A5 Q9Y345 1/20 0.51
MMP2 P08253 1/20 0.47
MMP9 P14780 1/20 0.47
SIRT6 Q8N6T7 1/20 0.46
SIRT1 Q96EB6 1/20 0.46
ITGAV P06756 1/20 0.44
TLR2 O60603 1/20 0.44
RELA Q04206 4/20 0.43
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
FOLH1 Q04609 1/20 0.42
CPB2 Q96IY4 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8760082 0.96 ITGB3 (0.53) ITGB3ITGA2BSLC6A5MMP2MMP9
SCHEMBL8728096 0.90 ITGB3 (0.51) ITGB3ITGA2BMMP2MMP9ITGAV
SCHEMBL6818957 0.90 ITGB3 (0.51) ITGB3ITGA2BITGAV
SCHEMBL8727473 0.90 ITGB3 (0.51) ITGB3ITGA2BMMP2MMP9ITGAV
SCHEMBL31522342 0.90 ITGB3 (0.51) ITGB3ITGA2BITGAV
SCHEMBL4059094 0.86 ITGB3 (0.51) ITGB3ITGA2BMMP2MMP9ITGAV
SCHEMBL7144039 0.85 ITGB3 (0.53) ITGB3ITGA2BSLC6A5MMP2MMP9
SCHEMBL7144029 0.85 ITGB3 (0.53) ITGB3ITGA2BSLC6A5MMP2MMP9
SCHEMBL28971870 0.82 SLC6A5 (0.50) ITGB3ITGA2BSLC6A5MMP2MMP9
SCHEMBL17509711 0.82 SLC6A5 (0.50) ITGB3ITGA2BSLC6A5MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0725057-B1 Alkylsulfonyl or alkylaminocarbonyl substituted lysine derivatives, process for their preparation, their use especially in cosmetics and compositions containing them OREAL (FR) 1997-01-15 EP claimed
EP-0725057-A1 Alkylsulfonyl or alkylaminocarbonyl substituted lysine derivatives, process for their preparation, their use especially in cosmetics and compositions containing them L'OREAL (FR) 1996-08-07 EP claimed
JP-8231493-A None JP disclosed
EP-0725057-B1 Alkylsulfonyl or alkylaminocarbonyl substituted lysine derivatives, process for their preparation, their use especially in cosmetics and compositions containing them OREAL (FR) 1997-01-15 EP disclosed
JP-H08231493-A LYSINE DERIVATIVE, ITS PRODUCTION AND COMPOSITION CONTAINING THE DERIVATIVE L'OREAL SA 1996-09-10 JP disclosed
EP-0725057-A1 Alkylsulfonyl or alkylaminocarbonyl substituted lysine derivatives, process for their preparation, their use especially in cosmetics and compositions containing them L'OREAL (FR) 1996-08-07 EP disclosed