Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632484 | 0.94 | TRPV1 (0.48) | TRPV1DUSP3 | |
| SCHEMBL5701277 | 0.92 | LPAR2 (0.50) | FAAHTRPV1LPAR3LPAR1LPAR2 | |
| SCHEMBL5701264 | 0.92 | LPAR2 (0.50) | FAAHTRPV1LPAR3LPAR1LPAR2 | |
| SCHEMBL5701269 | 0.92 | LPAR2 (0.50) | FAAHTRPV1LPAR3LPAR1LPAR2 | |
| SCHEMBL5701279 | 0.92 | LPAR2 (0.50) | FAAHTRPV1LPAR3LPAR1LPAR2 | |
| SCHEMBL5701240 | 0.86 | ALDH1A1 (0.51) | TRPV1DUSP3 | |
| SCHEMBL5701253 | 0.84 | ALDH1A1 (0.53) | TRPV1 | |
| SCHEMBL5701255 | 0.84 | ALDH1A1 (0.53) | TRPV1 | |
| SCHEMBL29121043 | 0.83 | FAAH (0.48) | FAAHTRPV1LPAR3LPAR1LPAR2 | |
| SCHEMBL21552396 | 0.79 | LPAR2 (0.50) | LPAR3LPAR1LPAR2MAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630877-B1 | Workup of Wittig reaction products | SHINETSU CHEMICAL CO (JP) | 1997-03-12 | — | — | EP | disclosed |
| EP-0630877-A1 | Workup of Wittig reaction products | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-5292973-A | Phosphine oxide removal from compounds formed by a Wittig reaction | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |