SCHEMBL8747654

SCHEMBL8747654

Cc1cc(CC(=O)Cl)cc(Cc2ccccc2)c1O

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.50
PTPN2 P17706 1/20 0.50
PTPN6 P29350 1/20 0.50
LDHA P00338 3/20 0.46
LDHB P07195 3/20 0.46
SHBG P04278 1/20 0.42
BCL2 P10415 2/20 0.42
BCL2L1 Q07817 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8747605 0.86 PTPN1 (0.48) PTPN1PTPN2PTPN6LDHALDHB
SCHEMBL31146662 0.82 SHBG (0.61) PTPN1PTPN2PTPN6LDHALDHB
SCHEMBL11519192 0.79 HMGB1 (0.46) SHBG
SCHEMBL9183572 0.78 PTPN1 (0.47) PTPN1PTPN2PTPN6LDHALDHB
SCHEMBL8822919 0.76 CYP3A4 (0.57) PTPN1PTPN2PTPN6LDHALDHB
SCHEMBL10906416 0.76 PTPN1 (0.60) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL544660 0.76 BCL2 (0.52) PTPN1PTPN2PTPN6LDHALDHB
SCHEMBL9196730 0.76 PTPN1 (0.45) PTPN1PTPN2PTPN6LDHALDHB
SCHEMBL11149189 0.75 BCL2 (0.47) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL10907295 0.73 PTPN1 (0.50) PTPN1PTPN2PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459950-B1 Stabilisation of dyes on polyamide fibres CIBA GEIGY AG (CH) 1997-03-12 EP disclosed
EP-0438381-B1 Stabilization of dyes on polyamide fibres CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
US-5356443-A Treating fiber before fixation step with sterically hindered phenol and sulfo containing compound CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
US-5181935-A THERMAL AND PHOTOCHEMICAL STABILIZATION OF DYEINGS ON POLYAMIDE FIBERS:STERICALLY HINDERED PHENOL AND ULTRA-VIOLET ABSORBER CIBA-GEIGY CORPORATION (US) 1993-01-26 US disclosed
US-5096456-A Exhaust or continuous dyeing; carpets automotive fabrics, brassiers CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0459950-A1 Stabilisation of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-12-04 EP disclosed
EP-0438381-A1 Stabilization of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed