Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3437085 | 0.84 | KDM4E (0.42) | KMT2AKDM4EALDH1A1SLC6A4HSD17B10 | |
| SCHEMBL8747769 | 0.83 | KMT2A (0.43) | KMT2APOLBMCOLN3KDM4EALDH1A1 | |
| SCHEMBL8748143 | 0.83 | POLB (0.50) | KMT2APOLBMCOLN3KDM4EALDH1A1 | |
| SCHEMBL8747756 | 0.83 | CFTR (0.53) | KMT2APOLBMCOLN3KDM4EALDH1A1 | |
| SCHEMBL8747734 | 0.81 | KMT2A (0.57) | KMT2APOLBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL12489097 | 0.79 | FFAR4 (0.47) | KDM4EALDH1A1MAPTHPGDSLC6A4 | |
| SCHEMBL16958853 | 0.77 | SLC6A4 (0.49) | KMT2AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7691521 | 0.77 | KMT2A (0.64) | KMT2APOLBMCOLN3KDM4EALDH1A1 | |
| SCHEMBL7696307 | 0.77 | ALDH1A1 (0.43) | POLBMCOLN3KDM4EALDH1A1MAPT | |
| SCHEMBL8747757 | 0.77 | POLB (0.47) | KMT2APOLBMCOLN3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1148385-A | 4-benzoylisoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-04-23 | — | — | CN | disclosed |
| EP-0759911-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031446-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-11-23 | — | — | WO | disclosed |