Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747768 | 0.87 | POLB (0.47) | POLBMCOLN3KMT2AKDM4EHSD17B10 | |
| SCHEMBL3437242 | 0.85 | CES2 (0.36) | POLBMCOLN3CES2CES1KDM4E | |
| SCHEMBL8747897 | 0.82 | POLB (0.50) | POLBMCOLN3KMT2AKDM4EHSD17B10 | |
| SCHEMBL8754753 | 0.78 | POLB (0.34) | POLBMCOLN3ALDH1A1MAPT | |
| SCHEMBL8747754 | 0.77 | KMT2A (0.43) | POLBMCOLN3KMT2AKDM4EHSD17B10 | |
| SCHEMBL7550294 | 0.76 | KMT2A (0.52) | POLBMCOLN3KMT2ACES2CES1 | |
| SCHEMBL8729538 | 0.75 | CES2 (0.44) | POLBMCOLN3KMT2ACES2CES1 | |
| SCHEMBL7554521 | 0.74 | KMT2A (0.43) | POLBMCOLN3KMT2ACES2CES1 | |
| SCHEMBL8748143 | 0.74 | POLB (0.50) | POLBMCOLN3KMT2AKDM4EHSD17B10 | |
| SCHEMBL27453108 | 0.73 | CES2 (0.42) | POLBMCOLN3KMT2ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759911-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031446-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-11-23 | — | — | WO | disclosed |