SCHEMBL8747962

SCHEMBL8747962

CN(C)CCC(=O)NN(C)C

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM7A Q6ZMT4 2/20 0.60
PHF8 Q9UPP1 2/20 0.60
KDM2A Q9Y2K7 2/20 0.60
TERT O14746 8/20 0.40
DNM1 Q05193 2/20 0.38
PAOX Q6QHF9 1/20 0.35
KDM4A O75164 6/20 0.34
KDM4C Q9H3R0 6/20 0.34
KDM5A P29375 1/20 0.34
MAPT P10636 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL584428 0.84 PHF8 (0.80) KDM7APHF8KDM2ADNM1MEN1
SCHEMBL25868621 0.80 KDM7A (0.46) KDM7APHF8KDM2ADNM1MAPT
SCHEMBL25868589 0.79 KDM7A (0.48) KDM7APHF8KDM2ADNM1MEN1
SCHEMBL1792763 0.77
SCHEMBL4774589 0.77
SCHEMBL10519966 0.77
SCHEMBL25393813 0.76 DNM1 (0.53) KDM7APHF8KDM2ADNM1MAPT
SCHEMBL2046233 0.75
SCHEMBL17047606 0.75 PHF8 (1.00) KDM7APHF8KDM2A
Succinic Acid SCHEMBL18497046 0.75 PHF8 (1.00) KDM7APHF8KDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023137227-A1 MULTI-VESICULAR LIPID NANOPARTICLE TOLEROGENIC VACCINES FOR INDUCTION OF SYSTEMIC IMMUNE TOLERANCE IN VIVO KARMA BIOTECHNOLOGIES (US) 2023-07-20 WO disclosed
EP-0619295-B1 PROCESS FOR PRODUCING N-MONOSUBSTITUTED (METH)ACRYLAMYDE KOHJIN CO (JP) 1997-03-12 EP disclosed
US-5587515-A Method of manufacturing N-monosubstituted (meth)acrylamides KOHJIN CO., LTD. (JP) 1996-12-24 US disclosed
EP-0619295-A1 PROCESS FOR PRODUCING N-MONOSUBSTITUTED (METH)ACRYLAMYDE KOHJIN CO. Ltd. (JP) 1994-10-12 EP disclosed
EP-0492464-A2 Reactive feed stream to replace inert blowing agent feed stream in a polyurethane foam process UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1992-07-01 EP disclosed
US-5084486-A Polymerization and blowing followed by molding UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1992-01-28 US disclosed