Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8748124 | 0.93 | APP (0.46) | APPGSRRNPEPBLMLMNA | |
| SCHEMBL584136 | 0.84 | LMNA (0.42) | APPBLMLMNASLC6A6CYP2C19 | |
| SCHEMBL28472596 | 0.83 | TP53 (0.36) | APPTP53LTA4HSLC22A6ENPEP | |
| SCHEMBL1133365 | 0.82 | LMNA (0.40) | APPBLMLMNASLC6A6CYP2C19 | |
| SCHEMBL28803665 | 0.81 | TP53 (0.59) | TP53DPP7 | |
| SCHEMBL28586828 | 0.81 | APP (0.54) | APPGSRRNPEPBLMLMNA | |
| SCHEMBL7552156 | 0.79 | TP53 (0.57) | BLMLMNATP53 | |
| SCHEMBL9657411 | 0.79 | TP53 (0.57) | BLMLMNATP53 | |
| SCHEMBL27662459 | 0.79 | TP53 (0.57) | BLMLMNATP53 | |
| SCHEMBL27784488 | 0.79 | TP53 (0.57) | BLMLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467856-B1 | Aminoalkanesulfonic acid derivatives and pharmaceutical compositions for use in preventing or treating heart diseases | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1997-03-19 | — | — | EP | claimed |
| EP-0467856-A2 | Aminoalkanesulfonic acid derivatives and pharmaceutical compositions for use in preventing or treating heart diseases | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1992-01-22 | — | — | EP | claimed |
| EP-0467856-B1 | Aminoalkanesulfonic acid derivatives and pharmaceutical compositions for use in preventing or treating heart diseases | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1997-03-19 | — | — | EP | disclosed |
| US-5430052-A | Protective effect against myocardial disorders caused by calcium ion overload; antiischemic agents; remedy for heart failure, angina pectoris | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| EP-0467856-A2 | Aminoalkanesulfonic acid derivatives and pharmaceutical compositions for use in preventing or treating heart diseases | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1992-01-22 | — | — | EP | disclosed |