SCHEMBL8748199

SCHEMBL8748199

C=CCOCCOc1cc[c]cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
THRB P10828 1/20 0.34
SLC5A1 P13866 1/20 0.34
SLC5A2 P31639 1/20 0.34
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
POLB P06746 1/20 0.32
KDM4E B2RXH2 2/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
MAPT P10636 1/20 0.31
APP P05067 4/20 0.30
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10842357 0.91 KCNA3 (0.38) CA12CA1CA2CA7CA9
Water SCHEMBL9510400 0.83 THRB (0.50) THRBALDH1A1MEN1KMT2AKDM4E
SCHEMBL482465 0.82 CA12 (0.48) CA12CA1CA2CA7CA9
SCHEMBL1596823 0.81 KCNA3 (0.52) THRBALDH1A1MEN1KMT2AKDM4E
SCHEMBL14004238 0.81 RARB (0.41) CA12CA1CA2CA7CA9
SCHEMBL10785918 0.79 KCNA3 (0.43) ALDH1A1KDM4EMAPK1TDP1MAPT
SCHEMBL31316456 0.79 THRB (0.50) THRBALDH1A1MEN1KMT2AKDM4E
SCHEMBL920853 0.79 ALDH1A1 (0.43) CA12CA1CA2CA7CA9
SCHEMBL920772 0.77 ALDH1A1 (0.54) THRBALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL10340654 0.77 THRB (0.36) THRBALDH1A1L3MBTL1KCNA3CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0534257-B1 Salicylic acid derivatives, the process for preparing the same and the heat-sensitive recording materials comprising thereof MITSUI TOATSU CHEMICALS (JP) 1997-03-12 EP disclosed
EP-0524419-B1 Heat-sensitive recording materials and phenol compounds MITSUI TOATSU CHEMICALS (JP) 1995-09-06 EP disclosed
US-5306688-A Color-forming, electron donating compound and electron accepting compound; storage stability of uncolored portion MITSUI TOATSU CHEMICALS, INC. (JP) 1994-04-26 US disclosed
US-5270281-A Chromogenic compound MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-12-14 US disclosed
EP-0534257-A1 Salicylic acid derivatives, the process for preparing the same and the heat-sensitive recording materials comprising thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
EP-0524419-A1 Heat-sensitive recording materials and phenol compounds MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-27 EP disclosed