SCHEMBL8748210

SCHEMBL8748210

C=Cc1ccccc1S(=O)(=O)OS(=O)(=O)c1ccccc1C=C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
TSHR P16473 2/20 0.33
HTT P42858 1/20 0.33
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KCNH2 Q12809 1/20 0.32
NFE2L2 Q16236 1/20 0.32
CA1 P00915 3/20 0.31
CA2 P00918 3/20 0.31
CA6 P23280 3/20 0.31
CA12 O43570 2/20 0.31
CA5A P35218 2/20 0.31
CA7 P43166 2/20 0.31
CA9 Q16790 2/20 0.31
CA5B Q9Y2D0 2/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5057784 0.84 ALDH1A1 (0.38) ALDH1A1TSHRHTTMEN1LMNA
SCHEMBL313949 0.84 ALDH1A1 (0.38) ALDH1A1TSHRHTTMEN1KMT2A
SCHEMBL2863586 0.81 ALDH1A1 (0.35) ALDH1A1TSHRHTTKCNH2NFE2L2
SCHEMBL1396538 0.80 ALDH1A1 (0.44) ALDH1A1TSHRHTTMEN1LMNA
SCHEMBL325853 0.80 ALDH1A1 (0.42) ALDH1A1TSHRLMNATDP1KCNH2
SCHEMBL4122680 0.80 ALDH1A1 (0.34) ALDH1A1KCNH2NFE2L2
SCHEMBL313316 0.80 ALDH1A1 (0.38) ALDH1A1KCNH2NFE2L2GAA
Silver SCHEMBL4962791 0.79 ALDH1A1 (0.40) ALDH1A1TSHRHTTMEN1LMNA
SCHEMBL10594900 0.78 ALDH1A1 (0.43) ALDH1A1TSHRHTTMEN1LMNA
SCHEMBL7172894 0.78 ALDH1A1 (0.33) ALDH1A1TSHRHTTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0761725-A2 Laminated polyester film DIAFOIL HOECHST CO., LTD (JP) 1997-03-12 EP disclosed