SCHEMBL8748225

SCHEMBL8748225

C[CH]SCCOc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.49
CHRNB2 P17787 2/20 0.48
CHRNB4 P30926 2/20 0.48
CHRNA3 P32297 2/20 0.48
CHRNA7 P36544 2/20 0.48
CHRNA4 P43681 2/20 0.48
HTR1B P28222 2/20 0.47
HTR1D P28221 1/20 0.47
ALDH1A1 P00352 3/20 0.47
TAAR1 Q96RJ0 1/20 0.47
RECQL P46063 1/20 0.47
LTA4H P09960 2/20 0.46
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
LMNA P02545 1/20 0.44
PKM P14618 1/20 0.43
TSHR P16473 1/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11285757 0.77 KCNA3 (0.58) KCNA3L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL14499849 0.76 KCNA3 (0.64) KCNA3L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL8671561 0.76 KCNA3 (0.64) KCNA3L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL11300555 0.74 KCNA3 (0.61) KCNA3L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL27515353 0.72 KCNA3 (0.58) KCNA3L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL28708338 0.72 KCNA3 (0.58) KCNA3L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL9808023 0.72 ALDH1A1 (0.61) KCNA3L3MBTL1ALDH1A1TAAR1RECQL
SCHEMBL1454209 0.72 KCNA3 (0.58) KCNA3CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL19542483 0.72 KCNA3 (0.58) KCNA3L3MBTL1CHRNB2CHRNB4CHRNA3
SCHEMBL27962 0.72 KCNA3 (0.82) KCNA3CHRNB2CHRNB4CHRNA3CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0534257-B1 Salicylic acid derivatives, the process for preparing the same and the heat-sensitive recording materials comprising thereof MITSUI TOATSU CHEMICALS (JP) 1997-03-12 EP disclosed
US-5306688-A Color-forming, electron donating compound and electron accepting compound; storage stability of uncolored portion MITSUI TOATSU CHEMICALS, INC. (JP) 1994-04-26 US disclosed
EP-0534257-A1 Salicylic acid derivatives, the process for preparing the same and the heat-sensitive recording materials comprising thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed