Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.58 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 2/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7244289 | 0.89 | KCNA3 (0.62) | KCNA3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL10985976 | 0.84 | LMNA (0.51) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL890350 | 0.83 | CHRNA7 (0.60) | KCNA3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL14499849 | 0.81 | KCNA3 (0.64) | KCNA3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL8671561 | 0.81 | KCNA3 (0.64) | KCNA3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL13461862 | 0.80 | DRD2 (0.52) | L3MBTL1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL13059256 | 0.80 | NPC1 (0.58) | CHRNB4CHRNA3CHRNA7L3MBTL1ALDH1A1 | |
| SCHEMBL11300555 | 0.79 | KCNA3 (0.61) | KCNA3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL3159603 | 0.78 | NPC1 (0.36) | KCNA3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL7934205 | 0.78 | KDM4E (0.49) | CHRNA7L3MBTL1ALDH1A1RECQLLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050440-A1 | Sulphonium compounds and herbicidal compositions containing them | FBC LIMITED (GB) | 1982-04-28 | — | — | EP | claimed |
| EP-2968440-B1 | CYTOTOXIC AND ANTI-MITOTIC COMPOUNDS, AND METHODS OF USING THE SAME | ZYMEWORKS INC (CA) | 2019-06-05 | — | — | EP | disclosed |
| WO-2017049402-A1 | MULTI-FUNCTIONAL ANTI-MICROBIAL POLYMERS AND COMPOSITIONS CONTAINING SAME | GHANDI KHASHAYAR (CA) | 2017-03-30 | — | — | WO | disclosed |
| US-8084644-B2 | Agricultural pesticide; Wide variety of compounds, for example phenyl N-phenyl-3-(phenylthio)thioacrylimidate; formula X-CH=CH-C(-Y)=N-Z where X, Y and Z are variable | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-27 | — | — | US | disclosed |
| US-8084644-B2 | Agricultural pesticide; Wide variety of compounds, for example phenyl N-phenyl-3-(phenylthio)thioacrylimidate; formula X-CH=CH-C(-Y)=N-Z where X, Y and Z are variable | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-27 | — | — | US | disclosed |
| EP-1313751-B1 | NEW MACROLIDES WITH ANTIBACTERIAL ACTIVITY | BASILEA PHARMACEUTICA AG (CH) | 2008-09-17 | — | — | EP | disclosed |
| EP-0050440-A1 | Sulphonium compounds and herbicidal compositions containing them | FBC LIMITED (GB) | 1982-04-28 | — | — | EP | disclosed |