SCHEMBL8748378

SCHEMBL8748378

Cc1cccc(C(=O)c2cc(N)ccc2-c2ccc(N)cc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.50
TUBB4A P04350 2/20 0.47
TUBB P07437 2/20 0.47
TUBA3C P0DPH7 2/20 0.47
TUBA1B P68363 2/20 0.47
TUBA4A P68366 2/20 0.47
TUBB4B P68371 2/20 0.47
TUBB3 Q13509 2/20 0.47
TUBB2A Q13885 2/20 0.47
TUBB8 Q3ZCM7 2/20 0.47
TUBA3E Q6PEY2 2/20 0.47
TUBA1A Q71U36 2/20 0.47
TUBA1C Q9BQE3 2/20 0.47
TUBB6 Q9BUF5 2/20 0.47
TUBB2B Q9BVA1 2/20 0.47
TUBB1 Q9H4B7 2/20 0.47
PARP1 P09874 1/20 0.46
CNR2 P34972 2/20 0.45
CYP2C8 P10632 1/20 0.44
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28436721 0.84 MAPT (0.49) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL3138403 0.83 CYP2C9 (0.53) POLBTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL11717599 0.82 POLB (0.55) POLBPARP1NPC1MITFLMNA
SCHEMBL6652575 0.78 MAPK13 (0.60) POLBPARP1CNR2NPC1MITF
SCHEMBL28431907 0.78 CDC25B (0.51) CYP2C8ALDH1A1MAPTKMT2AHPGD
SCHEMBL3138405 0.77 CYP2C9 (0.53) POLBTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL9973084 0.76 PBRM1 (0.69) POLBPARP1CNR2NPC1MITF
SCHEMBL28426167 0.74 SMN1; SMN2 (0.54) CYP2C8NPC1ALDH1A1MAPTKMT2A
SCHEMBL14134424 0.74 CNR2 (0.65) POLBTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL30341892 0.73 MAPT (0.54) CYP2C8NPC1LMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5569565-A Hologram recording material MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1996-10-29 US claimed
EP-0514786-B1 Hologram recording material, hologram recording device, method of manufacturing the same, and method of hologram recording MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1997-03-19 EP disclosed
US-5569565-A Hologram recording material MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1996-10-29 US disclosed
EP-0514786-A2 Hologram recording material, hologram recording device, method of manufacturing the same, and method of hologram recording MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1992-11-25 EP disclosed