Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847271 | 0.88 | PTGS2 (0.48) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL21941003 | 0.85 | MAPT (0.50) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8116858 | 0.84 | ALDH1A1 (0.49) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11442419 | 0.83 | ALDH1A1 (0.58) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7167102 | 0.83 | CXCR4 (0.49) | MAPTALDH1A1RECQLHSD17B10CA12 | |
| SCHEMBL11615334 | 0.83 | MAPT (0.54) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL28142388 | 0.82 | ALDH1A1 (0.64) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8114852 | 0.82 | MAPT (0.44) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL22071519 | 0.82 | CA12 (0.49) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8114849 | 0.82 | ALDH1A1 (0.46) | MAPTALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641308-B1 | PROCESS FOR PREPARING N-ALIPHATIC SUBSTITUTED P-PHENYLENEDIAMINES | MONSANTO CO (US) | 1997-03-12 | — | — | EP | disclosed |
| EP-0641308-A1 | PROCESS FOR PREPARING N-ALIPHATIC SUBSTITUTED P-PHENYLENEDIAMINES. | MONSANTO CO (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993024443-A1 | PROCESS FOR PREPARING N-ALIPHATIC SUBSTITUTED P-PHENYLENEDIAMINES | MONSANTO COMPANY (US) | 1993-12-09 | — | — | WO | disclosed |
| US-5252737-A | Process for preparing N-aliphatic substituted p-phenylenediamines | MONSANTO COMPANY (US) | 1993-10-12 | — | — | US | disclosed |