SCHEMBL874878

SCHEMBL874878

FC(F)(F)OB(OC(F)(F)F)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV6 Q9H1D0 3/20 0.40
ORAI1 Q96D31 2/20 0.40
ORAI2 Q96SN7 2/20 0.40
ORAI3 Q9BRQ5 2/20 0.40
ALDH1A1 P00352 2/20 0.36
TSHR P16473 2/20 0.36
CA4 P22748 2/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
ENPP2 Q13822 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
PCSK9 Q8NBP7 1/20 0.36
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
TRPM2 O94759 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29151345 0.85 CA4 (0.34) TRPV6ORAI1ORAI2ORAI3ALDH1A1
SCHEMBL7039000 0.76 TRPV6 (0.37) TRPV6ORAI1ORAI2ORAI3ALDH1A1
SCHEMBL483731 0.76 TRPV6 (0.45) TRPV6ORAI1ORAI2ORAI3ALDH1A1
SCHEMBL26451 0.75 TRPV6 (0.40) TRPV6ORAI1ORAI2ORAI3ALDH1A1
SCHEMBL8515031 0.75 TRPV6 (0.46) TRPV6ORAI1ORAI2ORAI3ALDH1A1
SCHEMBL2399022 0.72 TRPV6 (0.43) TRPV6ORAI1ORAI2ORAI3ALDH1A1
SCHEMBL1221793 0.70 TRPV6 (0.46) TRPV6ORAI1ORAI2ORAI3ALDH1A1
SCHEMBL12062026 0.70 TRPV6 (0.36) TRPV6ORAI1ORAI2ORAI3ALDH1A1
SCHEMBL14947429 0.67 TRPV6 (0.33) TRPV6ORAI1ORAI2ORAI3ALDH1A1
SCHEMBL4600384 0.67 TSHR (0.36) ALDH1A1TSHRCA4CA5ACA5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118878402-A Preparation method of trifluoromethyl ketone compound based on palladium catalysis of C-N bond cleavage 大连理工大学 2024-11-01 CN claimed
CN-118344378-A Beta-axis chiral porphyrin compound and preparation method thereof through Suzuki coupling reaction 同济大学 2024-07-16 CN claimed
CN-118307536-A 4, 7-Bis (3, 5-bis (trifluoromethyl) phenyl) -1, 10-phenanthroline framework ligand and synthesis method and application thereof 浙江工业大学 2024-07-09 CN claimed
CN-118084682-A Tetraphenylenediamine monomer containing trifluoromethyl and preparation method and application thereof 株洲时代新材料科技股份有限公司 2024-05-28 CN claimed
CN-113621215-B Preparation method of organic-inorganic hybrid biomass phenolic resin ablation-resistant material 哈尔滨工业大学 2024-02-09 CN claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
CN-116916755-A Materials and methods for extending the shelf life of food products JP实验室公司 2023-10-20 CN claimed
CN-116514651-B Amphiphilic aggregation-induced emission material fluorescent probe and application thereof 北京市疾病预防控制中心 2023-09-05 CN claimed
CN-116514651-A Amphiphilic aggregation-induced emission material fluorescent probe and application thereof 北京市疾病预防控制中心 2023-08-01 CN claimed
CN-116231081-A Electrolyte additive, electrolyte containing same and lithium metal battery 山东大学 2023-06-06 CN claimed
CN-114195812-A Method for synthesizing 2, 4-bis (trifluoromethyl) phenylboronic acid 大连联化化学有限公司 2022-03-18 CN claimed
CN-113621215-A Preparation method of organic-inorganic hybrid biomass phenolic resin ablation-resistant material 哈尔滨工业大学 2021-11-09 CN claimed
CN-107854973-B Modified polyphenyl ether gas separation membrane and preparation method thereof 青岛大学 2021-04-23 CN claimed
CN-112687878-A Electrochemical device and electronic device 东莞新能源科技有限公司 2021-04-20 CN claimed
CN-112500297-A Bis-trifluoromethyl-benzene-substituted asymmetric meta-aromatic diamine monomer and preparation method thereof 常州大学 2021-03-16 CN claimed
CN-111808434-A Method for preparing naphthol AS series azo dye 青岛科技大学 2020-10-23 CN claimed
CN-111574450-A Novel chiral biphenyl quaternary ammonium salt phase transfer catalyst and preparation method and application thereof 广东工业大学 2020-08-25 CN claimed
CN-108503571-B Synthetic method of vildagliptin 无锡科华生物科技有限公司 2020-07-14 CN claimed
CN-111303150-A High-efficiency narrow-half-peak-width aggregation state luminescent material 苏州大学 2020-06-19 CN claimed
WO-2015145333-A1 PROCESS FOR THE PREPARATION OF SITAGLIPTIN AND ITS INTERMEDIATE SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2015-10-01 WO claimed