SCHEMBL483731

SCHEMBL483731

OB(OC(F)(F)F)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TRPV6 Q9H1D0 5/20 0.45
ORAI1 Q96D31 4/20 0.44
ORAI2 Q96SN7 4/20 0.44
ORAI3 Q9BRQ5 4/20 0.44
PCSK9 Q8NBP7 2/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
ENPP2 Q13822 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
MGLL Q99685 4/20 0.36
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CES1 P23141 2/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28830120 0.79 TRPV6 (0.40) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL2492717 0.78 ENPP2 (0.48) TRPV6ORAI1ORAI2ORAI3ENPP2
SCHEMBL28474744 0.78 CA2 (0.48) TRPV6ORAI1ORAI2ORAI3CA5A
SCHEMBL874879 0.78 TRPV6 (0.42) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL26452 0.77 TRPV6 (0.44) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL8515033 0.77 TRPV6 (0.44) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL12615910 0.77 NPC1 (0.36) MGLLALDH1A1
SCHEMBL17767360 0.77 TRPV6 (0.38) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL874878 0.76 TRPV6 (0.40) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL25376692 0.76 TRPV6 (0.42) TRPV6ORAI1ORAI2ORAI3PCSK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 508 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122060240-A Long-acting antistatic PE packaging film material and preparation method thereof 广州星辰包装有限公司 2026-05-19 CN claimed
US-12221435-B2 Organic molecules, in particular for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2025-02-11 US claimed
CN-118878402-A Preparation method of trifluoromethyl ketone compound based on palladium catalysis of C-N bond cleavage 大连理工大学 2024-11-01 CN claimed
CN-118344378-A Beta-axis chiral porphyrin compound and preparation method thereof through Suzuki coupling reaction 同济大学 2024-07-16 CN claimed
CN-118307536-A 4, 7-Bis (3, 5-bis (trifluoromethyl) phenyl) -1, 10-phenanthroline framework ligand and synthesis method and application thereof 浙江工业大学 2024-07-09 CN claimed
CN-118084682-A Tetraphenylenediamine monomer containing trifluoromethyl and preparation method and application thereof 株洲时代新材料科技股份有限公司 2024-05-28 CN claimed
CN-117865773-A Preparation method of difluoromethyl aromatic compound based on palladium-catalyzed decarbonylation coupling 大连理工大学 2024-04-12 CN claimed
CN-113621215-B Preparation method of organic-inorganic hybrid biomass phenolic resin ablation-resistant material 哈尔滨工业大学 2024-02-09 CN claimed
CN-116981678-A Method for synthesizing reactive carbohydrates comprising antigen precursors for conjugation to a carrier material 科兰克斯资本 2023-10-31 CN claimed
CN-116916755-A Materials and methods for extending the shelf life of food products JP实验室公司 2023-10-20 CN claimed
CN-110799625-A Organic molecules, in particular for optoelectronic devices 辛诺拉有限公司 2020-02-14 CN claimed
CN-107074675-B Preparation method of chiral 2- [ 1-cyclopropylethyl ] -6-isopropyl-phenol 四川海思科制药有限公司 2019-12-20 CN claimed
CN-107108416-B Preparation method of 1, 2-dicyclopropylethylphenol and optical isomer thereof 四川海思科制药有限公司 2019-12-20 CN claimed
WO-2019053049-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-03-21 WO claimed
WO-2015145333-A1 PROCESS FOR THE PREPARATION OF SITAGLIPTIN AND ITS INTERMEDIATE SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2015-10-01 WO claimed
EP-2059227-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY Aeris Therapeutics, Inc. (US) 2009-05-20 EP claimed
WO-2008039827-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY AERIS THERAPEUTICS, INC. (US) 2008-04-03 WO claimed
EP-1313560-A4 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION UNIV YALE (US) 2005-02-09 EP claimed
EP-1313560-A1 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION YALE UNIVERSITY (US) 2003-05-28 EP claimed
WO-2002011883-A1 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION YALE UNIVERSITY (US) 2002-02-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12221435-B2 Organic molecules, in particular for use in optoelectronic devices OR10J3, EPCAM, OR51E2 TRPV6 497/4885ORAI1 1759/4885ORAI2 80/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.