SCHEMBL8748944

SCHEMBL8748944

CCCCCCCCCCCCCCCCCCN1C(=O)CCC1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
POLB P06746 1/20 0.51
PTGER4 P35408 12/20 0.51
PTGER3 P43115 8/20 0.51
PTGER2 P43116 8/20 0.51
ALDH1A1 P00352 1/20 0.46
GBA1 P04062 1/20 0.44
ACE P12821 2/20 0.41
FAAH O00519 1/20 0.41
MGLL Q99685 1/20 0.41
USP2 O75604 1/20 0.40
KCNH2 Q12809 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9151061 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL242586 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8761679 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL3425106 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8761610 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8748862 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8761736 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8749215 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8754825 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8748934 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105592721-A Organic compounds GIVAUDAN SA 2016-05-18 CN claimed
EP-0342056-B1 Cosmetic composition UNILEVER PLC (GB) 1994-08-17 EP claimed
EP-0277428-B1 Cosmetic composition UNILEVER PLC (GB) 1994-03-23 EP claimed
EP-0342055-B1 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1994-01-12 EP claimed
EP-0342056-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342055-A2 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP claimed
CN-105592721-A Organic compounds GIVAUDAN SA 2016-05-18 CN disclosed
EP-0446047-B1 Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors UNILEVER PLC (GB) 1997-06-11 EP disclosed
EP-0571198-B1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1997-03-19 EP disclosed
EP-0572167-B1 Cosmetic composition UNILEVER PLC (GB) 1996-10-09 EP disclosed
US-5559092-A HAIR GROWTH, GLUTAMINE DIPEPTIDE CHESEBROUGH-POND'S USA CO. DIVISION OF CONOPCO, INC. (US) 1996-09-24 US disclosed
EP-0490581-B1 Cosmetic composition UNILEVER PLC (GB) 1996-05-22 EP disclosed
EP-0335554-A2 Cosmetic composition UNILEVER PLC (GB) 1989-10-04 EP disclosed
EP-0334586-A1 Carbohydrate lactam derivatives and their use in cosmetic compositions UNILEVER PLC (GB) 1989-09-27 EP disclosed
EP-0334585-A2 Cosmetic composition UNILEVER PLC (GB) 1989-09-27 EP disclosed
US-4832946-A CELL CULTURE FOR HAIR GROWTH CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC., A CORP. OF NY 1989-05-23 US disclosed
EP-0295092-A2 Skin treatment composition UNILEVER PLC (GB) 1988-12-14 EP disclosed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP disclosed
EP-0272920-A1 Cosmetic composition UNILEVER PLC (GB) 1988-06-29 EP disclosed