SCHEMBL242586

SCHEMBL242586

CCCCCCCCCCCCN1C(=O)CCC1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
POLB P06746 1/20 0.51
PTGER4 P35408 12/20 0.51
PTGER3 P43115 8/20 0.51
PTGER2 P43116 8/20 0.51
ALDH1A1 P00352 1/20 0.46
GBA1 P04062 1/20 0.44
ACE P12821 2/20 0.41
FAAH O00519 1/20 0.41
MGLL Q99685 1/20 0.41
USP2 O75604 1/20 0.40
KCNH2 Q12809 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9151061 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8761679 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8748944 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL3425106 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8761610 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8748862 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8761736 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8749215 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8754825 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8748934 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0342056-B1 Cosmetic composition UNILEVER PLC (GB) 1994-08-17 EP claimed
EP-0277428-B1 Cosmetic composition UNILEVER PLC (GB) 1994-03-23 EP claimed
EP-0342055-B1 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1994-01-12 EP claimed
EP-0342054-B1 Cosmetic composition UNILEVER PLC (GB) 1993-11-03 EP claimed
US-5118692-A Penetration enhances for transdermal delivery of systemic agents WHITBY RESEARCH, INC. (US) 1992-06-02 US claimed
US-5118676-A Administering carboxylic derivatives as enhancer with systemically active agents WHITBY RESEARCH, INC. (US) 1992-06-02 US claimed
WO-1989011275-A1 PENETRATION ENHANCERS FOR TRANSDERMAL DELIVERY OF SYSTEMIC AGENTS NELSON RESEARCH & DEVELOPMENT CO. (US) 1989-11-30 WO claimed
EP-0342054-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342055-A2 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342056-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP claimed
US-12589095-B2 Unit dosage form for transmucosal drug delivery of an active pharmaceutical ingredient PRIMO PHARMATECH LLC (US) 2026-03-31 US disclosed
US-12558312-B2 Solid dosage form for transmucosal drug delivery PRIMO PHARMATECH LLC (US) 2026-02-24 US disclosed
EP-3735988-B1 SUBLINGUAL FILMS SUMITOMO PHARMA AMERICA INC (US) 2026-02-04 EP disclosed
EP-4578461-A2 METHODS OF TREATING PARKINSONS DISEASE BY ADMINISTRATION OF APOMORPHINE TO AN ORAL MUCOSA Sumitomo Pharma America, Inc. (US) 2025-07-02 EP disclosed
EP-0334586-A1 Carbohydrate lactam derivatives and their use in cosmetic compositions UNILEVER PLC (GB) 1989-09-27 EP disclosed
US-4832946-A CELL CULTURE FOR HAIR GROWTH CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC., A CORP. OF NY 1989-05-23 US disclosed
EP-0295092-A2 Skin treatment composition UNILEVER PLC (GB) 1988-12-14 EP disclosed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP disclosed
EP-0272920-A1 Cosmetic composition UNILEVER PLC (GB) 1988-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12589095-B2 Unit dosage form for transmucosal drug delivery of an active pharmaceutical ingredient OXTR, CCKBR, HTR2B MEN1 971/4885KMT2A 4082/4885POLB 3383/4885
US-12558312-B2 Solid dosage form for transmucosal drug delivery AANAT, MTNR1B, CHLSN MEN1 378/4885KMT2A 2264/4885POLB 2483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.