SCHEMBL8761679

SCHEMBL8761679

CCCCCCCCCCN1C(=O)CCC1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.51
▸ KMT2A Q03164 2/20 0.51
▸ POLB P06746 1/20 0.51
▸ PTGER4 P35408 12/20 0.51
▸ PTGER3 P43115 8/20 0.51
▸ PTGER2 P43116 8/20 0.51
▸ ALDH1A1 P00352 1/20 0.46
▸ GBA1 P04062 1/20 0.44
▸ ACE P12821 2/20 0.41
▸ FAAH O00519 1/20 0.41
▸ MGLL Q99685 1/20 0.41
▸ USP2 O75604 1/20 0.40
▸ KCNH2 Q12809 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8761736 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8754825 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8748862 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8749186 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8761610 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8748934 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL242586 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8748944 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL9151061 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL3425106 1.00 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES Ananda Scientific, Inc. (US) 2025-06-19 — — US disclosed
US-10577319-B2 Process for preparing alkyl pyroglutamic acids DOW GLOBAL TECHNOLOGIES LLC (US) 2020-03-03 — — US disclosed
US-20180201578-A1 PROCESS FOR PREPARING ALKYL PYROGLUTAMIC ACIDS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-07-19 — — US disclosed
US-20180201578-A1 PROCESS FOR PREPARING ALKYL PYROGLUTAMIC ACIDS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-07-19 — — US disclosed
EP-2763964-B1 PROCESS FOR PREPARING ALKYL PYROGLUTAMIC ACIDS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-05-16 — — EP disclosed
US-20160237033-A1 PROCESS FOR PREPARING ALKYL PYROGLUTAMIC ACIDS DOW GLOBAL TECHNOLOGIES LLC (US) 2016-08-18 — — US disclosed
US-20160237033-A1 PROCESS FOR PREPARING ALKYL PYROGLUTAMIC ACIDS DOW GLOBAL TECHNOLOGIES LLC (US) 2016-08-18 — — US disclosed
US-9260388-B2 Process for preparing alkyl pyroglutamic acids DOW GLOBAL TECHNOLOGIES LLC (US) 2016-02-16 — — US disclosed
US-9260388-B2 Process for preparing alkyl pyroglutamic acids DOW GLOBAL TECHNOLOGIES LLC (US) 2016-02-16 — — US disclosed
US-20140342966-A1 PROCESS FOR PREPARING ALKYL PYROGLUTAMIC ACIDS DOW GLOBAL TECHNOLOGIES LLC 2014-11-20 — — US disclosed
US-5472946-A Topical administration of lincomycin, clindamycin, erthromycin and iododeoxyuridine on skin or mucuous membranes DISCOVERY THERAPEUTICS, INC. 1995-12-05 — — US disclosed
US-5470848-A Penetration enhancers for transdermal delivery of systemic agents DISCOVERY THERAPEUTICS, INC. 1995-11-28 — — US disclosed
US-5444075-A Penetration enhancers for transdermal delivery of systemic agents MINASKANIAN GEVORK (US) 1995-08-22 — — US disclosed
US-5411978-A Aging resistance, human skin CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1995-05-02 — — US disclosed
US-5338747-A Benzoisothiazolinone-1-dioxide derivatives as elastase inhibitors CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1994-08-16 — — US disclosed
US-5234959-A Omega-dialkylaminoalkanoic acids; drug delivery directly to the bloodstream WHITBY RESEARCH, INC. (US) 1993-08-10 — — US disclosed
US-5118692-A Penetration enhances for transdermal delivery of systemic agents WHITBY RESEARCH, INC. (US) 1992-06-02 — — US disclosed
US-5118676-A Administering carboxylic derivatives as enhancer with systemically active agents WHITBY RESEARCH, INC. (US) 1992-06-02 — — US disclosed
EP-0446047-A1 Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors UNILEVER PLC (GB) 1991-09-11 — — EP disclosed
US-4996199-A Penetration enhancers for transdermal delivery of systemic agents WHITBY RESEARCH, INC. (US) 1991-02-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10577319-B2 Process for preparing alkyl pyroglutamic acids GRHPR, GLO1, GCG MEN1 1122/4885KMT2A 2249/4885POLB 218/4885
US-20160237033-A1 PROCESS FOR PREPARING ALKYL PYROGLUTAMIC ACIDS GRHPR, GLO1, GCG MEN1 1122/4885KMT2A 2249/4885POLB 218/4885
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES CNR2, CNR1, FAAH MEN1 4840/4885KMT2A 2718/4885POLB 2615/4885
US-20180201578-A1 PROCESS FOR PREPARING ALKYL PYROGLUTAMIC ACIDS GRHPR, GLO1, GCG MEN1 1122/4885KMT2A 2249/4885POLB 218/4885
US-20140342966-A1 PROCESS FOR PREPARING ALKYL PYROGLUTAMIC ACIDS GLO1, PLOD1, GRHPR MEN1 1094/4885KMT2A 2713/4885POLB 207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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