Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11088603 | 0.98 | ALDH1A1 (0.43) | ALDH1A1CYP3A4GAATHRBHSD17B10 | |
| SCHEMBL9139396 | 0.84 | TSHR (0.46) | ALDH1A1CYP3A4HSD17B10GPR35TSHR | |
| SCHEMBL8069993 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CYP3A4HSD17B10KMT2AMEN1 | |
| SCHEMBL9703411 | 0.80 | TSHR (0.54) | ALDH1A1CYP3A4HSD17B10KMT2AMEN1 | |
| SCHEMBL8311313 | 0.80 | GAA (0.55) | ALDH1A1CYP3A4GAATHRBHSD17B10 | |
| SCHEMBL23152122 | 0.77 | ALDH1A1 (0.44) | ALDH1A1CYP3A4HSD17B10KMT2AMEN1 | |
| SCHEMBL102206 | 0.77 | TSHR (0.45) | ALDH1A1HSD17B10GPR35KMT2AMEN1 | |
| SCHEMBL2371812 | 0.77 | TSHR (0.52) | ALDH1A1CYP3A4GAATHRBHSD17B10 | |
| SCHEMBL31330060 | 0.77 | ALDH1A1 (0.42) | ALDH1A1CYP3A4HSD17B10KMT2AMEN1 | |
| SCHEMBL28187713 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP3A4HSD17B10GPR35TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659399-B1 | Process of direct hair using steam | OREAL (FR) | 1997-03-19 | — | — | EP | claimed |
| US-5496377-A | HAIR DYES, NITRO-AMINE COMPOUNDS | L'OREAL (FR) | 1996-03-05 | — | — | US | claimed |
| EP-0659399-A1 | Process of direct hair using steam | L'OREAL (FR) | 1995-06-28 | — | — | EP | claimed |
| EP-0659399-B1 | Process of direct hair using steam | OREAL (FR) | 1997-03-19 | — | — | EP | disclosed |
| US-5496377-A | HAIR DYES, NITRO-AMINE COMPOUNDS | L'OREAL (FR) | 1996-03-05 | — | — | US | disclosed |
| EP-0659399-A1 | Process of direct hair using steam | L'OREAL (FR) | 1995-06-28 | — | — | EP | disclosed |
| US-4473374-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1984-09-25 | — | — | US | disclosed |
| US-4425132-A | HAIR DYES, APPLYING WITHOUT RINSING | L'OREAL (FR) | 1984-01-10 | — | — | US | disclosed |
| US-4330291-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-05-18 | — | — | US | disclosed |