Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27851139 | 0.85 | GAA (0.57) | GAATHRBMAPK1ALOX15HSD17B10 | |
| SCHEMBL29652066 | 0.82 | GPR35 (0.54) | GAATHRBMAPK1ALOX15HSD17B10 | |
| SCHEMBL16210823 | 0.80 | GAA (0.52) | GAATHRBMAPK1ALOX15HSD17B10 | |
| SCHEMBL8749133 | 0.80 | ALDH1A1 (0.44) | GAATHRBMAPK1HSD17B10GPR35 | |
| SCHEMBL2371812 | 0.80 | TSHR (0.52) | GAATHRBHSD17B10GPR35MEN1 | |
| SCHEMBL27832802 | 0.79 | MEN1 (0.53) | GAATHRBALOX15MEN1KMT2A | |
| SCHEMBL31634614 | 0.79 | GAA (0.55) | GAATHRBMAPK1ALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL11088603 | 0.79 | ALDH1A1 (0.43) | GAATHRBMAPK1HSD17B10GPR35 | |
| SCHEMBL15962080 | 0.77 | TDP1 (0.57) | GAATHRBALOX15GPR35MEN1 | |
| SCHEMBL70085 | 0.77 | GPR35 (0.59) | MAPK1ALOX15HSD17B10L3MBTL1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4246052-A | REDUCED AND DIAZOTIZED TO FORM THE IGNITING AGENTS FOR PRIMERS AND EXPLOSIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-20 | — | — | US | claimed |
| CN-1159303-C | Preparation of intermediate for monocyclic beta-lactams derivatives | ER | 2004-07-28 | — | — | CN | disclosed |
| CN-1067053-C | A process for preparing the intermediate of the derivatives of monocycle beta-lactam antibiotics | SQUIBB & SONS INC (US) | 2001-06-13 | — | — | CN | disclosed |
| CN-1251836-A | Preparation of intermediate for monocyclic beta-lactams derivatives | SQUIBB & SONS INC (US) | 2000-05-03 | — | — | CN | disclosed |
| EP-0484881-B1 | Heteroaroyl derivatives of monocyclic beta-lactam antibiotics | SQUIBB & SONS INC (US) | 1999-04-07 | — | — | EP | disclosed |
| US-5705645-A | Hereroaryl derivatives of monocyclic beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1998-01-06 | — | — | US | disclosed |
| CN-1031825-C | Process for the preparation of heteroaroyl derivatives of monocyclic beta-lactam antibiotics | SQUIBB & SONS INC (US) | 1996-05-22 | — | — | CN | disclosed |
| CN-1113228-A | A process for preparing the intermediate of the derivatives of monocycle beta-lactam antibiotics | SQUIBB & SONS INC (US) | 1995-12-13 | — | — | CN | disclosed |
| US-5420277-A | BACTERICIDE INTERMEDIATES | E. R. SQUIBB & SONS, INC. (US) | 1995-05-30 | — | — | US | disclosed |
| US-5290929-A | Heteroaryl derivatives of monocyclic beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1994-03-01 | — | — | US | disclosed |
| CN-1061414-A | HETEROAROYL DERIVATIVES OF MONOCYCLIC BETA-LACTAM ANTIBIOTICS | SQUIBB & SONS INC (US) | 1992-05-27 | — | — | CN | disclosed |
| EP-0484881-A2 | Heteroaroyl derivatives of monocyclic beta-lactam antibiotics | E.R. SQUIBB & SONS, INC. (US) | 1992-05-13 | — | — | EP | disclosed |
| US-4246052-A | REDUCED AND DIAZOTIZED TO FORM THE IGNITING AGENTS FOR PRIMERS AND EXPLOSIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-20 | — | — | US | disclosed |
| US-4246052-A | REDUCED AND DIAZOTIZED TO FORM THE IGNITING AGENTS FOR PRIMERS AND EXPLOSIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-20 | — | — | US | disclosed |