Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KIF5B | P33176 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954578 | 0.84 | THRA (0.46) | THRATHRBCYP3A4RETKIF5B | |
| SCHEMBL30812029 | 0.84 | THRA (0.46) | THRATHRBCYP3A4RETKIF5B | |
| SCHEMBL17606538 | 0.83 | SLC6A4 (0.46) | KDRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30564867 | 0.83 | SLC6A4 (0.46) | KDRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL806364 | 0.80 | TSHR (0.42) | CA12ALDH1A1CA2LMNASLC6A2 | |
| SCHEMBL8693307 | 0.78 | CYP3A4 (0.48) | THRATHRBCYP3A4RETKIF5B | |
| SCHEMBL10588387 | 0.77 | PARP10 (0.47) | ESR1ESR2CYP3A4RAB9ACA12 | |
| SCHEMBL11091487 | 0.75 | MAPK1 (0.57) | THRATHRBCYP3A4ALDH1A1LMNA | |
| SCHEMBL24506246 | 0.74 | MAPT (0.58) | THRATHRBF10ESR1ESR2 | |
| SCHEMBL11826075 | 0.74 | LTA4H (0.50) | CYP3A4CA12ALDH1A1CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151696-A | Antibacterial agent | DAIICHI SEIYAKU CO (JP) | 1997-06-11 | — | — | CN | disclosed |
| EP-0768085-A1 | ANTIBACTERIAL AGENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |
| EP-0761215-A1 | ANTIBACTERIAL AGENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |