Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.42 |
| ▸ | PPM1B | O75688 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1619445 | 1.00 | LMNA (0.52) | LMNAGAATSHRCNR1DAGLA | |
| SCHEMBL12909848 | 0.90 | LMNA (0.50) | LMNAGAATSHRCNR1DAGLA | |
| SCHEMBL813807 | 0.90 | LMNA (0.50) | LMNAGAATSHRCNR1DAGLA | |
| SCHEMBL6205684 | 0.90 | LMNA (0.50) | LMNAGAATSHRCNR1DAGLA | |
| SCHEMBL1619527 | 0.90 | GAA (0.55) | LMNAGAATSHRCNR1DAGLA | |
| SCHEMBL6686852 | 0.89 | LMNA (0.49) | LMNAGAATSHRCNR1DAGLA | |
| SCHEMBL6686850 | 0.89 | LMNA (0.49) | LMNAGAATSHRCNR1DAGLA | |
| SCHEMBL10353311 | 0.88 | CNR1 (0.49) | LMNAGAATSHRCNR1DAGLA | |
| SCHEMBL10353701 | 0.88 | CNR1 (0.49) | LMNAGAATSHRCNR1DAGLA | |
| SCHEMBL1978841 | 0.88 | CNR1 (0.49) | LMNAGAATSHRCNR1DAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397519-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1994-11-09 | — | — | EP | claimed |
| EP-0342056-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1994-08-17 | — | — | EP | claimed |
| EP-0277428-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1994-03-23 | — | — | EP | claimed |
| EP-0342055-B1 | Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis | UNILEVER PLC (GB) | 1994-01-12 | — | — | EP | claimed |
| EP-0342054-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1993-11-03 | — | — | EP | claimed |
| US-5137714-A | Anhydrous cosmetic composition comprising stable lower alkyl esters of pyroglutamic acid | UNILEVER PATENT HOLDINGS B.V. (NL) | 1992-08-11 | — | — | US | claimed |
| EP-0397519-A1 | Cosmetic composition | UNILEVER PLC (GB) | 1990-11-14 | — | — | EP | claimed |
| EP-0342056-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1989-11-15 | — | — | EP | claimed |
| EP-0342054-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1989-11-15 | — | — | EP | claimed |
| EP-0342055-A2 | Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis | UNILEVER PLC (GB) | 1989-11-15 | — | — | EP | claimed |
| EP-0277428-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1988-08-10 | — | — | EP | claimed |
| EP-0446047-B1 | Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors | UNILEVER PLC (GB) | 1997-06-11 | — | — | EP | disclosed |
| EP-0571198-B1 | Cosmetic composition containing hair-growth promoter | UNILEVER PLC (GB) | 1997-03-19 | — | — | EP | disclosed |
| EP-0572167-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1996-10-09 | — | — | EP | disclosed |
| US-5559092-A | HAIR GROWTH, GLUTAMINE DIPEPTIDE | CHESEBROUGH-POND'S USA CO. DIVISION OF CONOPCO, INC. (US) | 1996-09-24 | — | — | US | disclosed |
| US-4832946-A | CELL CULTURE FOR HAIR GROWTH | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC., A CORP. OF NY | 1989-05-23 | — | — | US | disclosed |
| EP-0295092-A2 | Skin treatment composition | UNILEVER PLC (GB) | 1988-12-14 | — | — | EP | disclosed |
| US-4789667-A | ANTIINFLAMMATORY AGENT AND PYROGLUTAMATES AS PENETRATION ENHANCERS | TEIJIN LIMITED (JP) | 1988-12-06 | — | — | US | disclosed |
| EP-0277428-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1988-08-10 | — | — | EP | disclosed |
| EP-0272920-A1 | Cosmetic composition | UNILEVER PLC (GB) | 1988-06-29 | — | — | EP | disclosed |