SCHEMBL8749457

SCHEMBL8749457

CCCCC(CC)C(=O)Nc1cccc([C]=O)c1

nearest known ligand 0.66

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.61
MEN1 O00255 2/20 0.61
ALDH1A1 P00352 1/20 0.61
MAPT P10636 1/20 0.61
MAPK1 P28482 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
LMNA P02545 2/20 0.58
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA7 P43166 1/20 0.52
CA14 Q9ULX7 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51
TSHR P16473 3/20 0.45
HSD17B10 Q99714 1/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25681987 0.88 KMT2A (0.72) KMT2AMEN1ALDH1A1MAPTMAPK1
SCHEMBL15604014 0.82 ALDH1A1 (0.64) KMT2AMEN1ALDH1A1MAPTMAPK1
SCHEMBL25000794 0.82 KMT2A (0.64) KMT2AMEN1ALDH1A1MAPTMAPK1
SCHEMBL3923314 0.81 MEN1 (0.89) KMT2AMEN1ALDH1A1MAPTMAPK1
SCHEMBL8749459 0.80 KMT2A (0.61) KMT2AMEN1ALDH1A1MAPTMAPK1
SCHEMBL10470242 0.80 LMNA (0.62) KMT2AMEN1ALDH1A1MAPTMAPK1
SCHEMBL10470243 0.80 KMT2A (0.61) KMT2AMEN1ALDH1A1MAPTMAPK1
SCHEMBL11652739 0.79 MEN1 (0.86) KMT2AMEN1ALDH1A1MAPTMAPK1
SCHEMBL12245070 0.79 LMNA (0.67) KMT2AMEN1ALDH1A1MAPTMAPK1
SCHEMBL21670257 0.79 RXFP1 (0.61) KMT2AMEN1ALDH1A1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459349-B1 Silver halide color negative photosensitive material FUJI PHOTO FILM CO LTD (JP) 1997-03-26 EP disclosed
US-5254446-A Pyrazoloazole magenta coupler; sharpness FUJI PHOTO FILM CO., LTD. (JP) 1993-10-19 US disclosed
EP-0459349-A1 Silver halide color negative photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-12-04 EP disclosed
EP-0456257-A1 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-11-13 EP disclosed