Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4838670 | 0.85 | ALDH1A1 (0.41) | SLC7A5ADRA1AADRA1BEGFRKCNA5 | |
| SCHEMBL29531759 | 0.84 | SLC7A5 (0.41) | SLC7A5ADRA1AADRA1BNR1H2HMGB1 | |
| SCHEMBL27503212 | 0.84 | TSHR (0.39) | SLC7A5ADRA1AADRA1BEGFRNR1H2 | |
| SCHEMBL4520357 | 0.84 | SLC7A5 (0.41) | SLC7A5ADRA1AADRA1BNR1H2HMGB1 | |
| Hydrochloric Acid SCHEMBL4838664 | 0.84 | ALDH1A1 (0.41) | SLC7A5ADRA1AADRA1BEGFRKCNA5 | |
| SCHEMBL27637322 | 0.82 | CTSD (0.43) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL19126688 | 0.81 | SLC7A5 (0.36) | SLC7A5ADRA1AADRA1BEGFRNR1H2 | |
| SCHEMBL5841080 | 0.79 | SLC7A5 (0.42) | SLC7A5NR1H2HMGB1RXRANR1H3 | |
| SCHEMBL7451046 | 0.76 | ALDH1A1 (0.33) | SLC7A5ADRA1AADRA1BNR1H2RXRA | |
| SCHEMBL5697877 | 0.76 | ALDH1A1 (0.46) | ADRA1AADRA1BHMGB1GRM6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763016-A1 | COMPOSITIONS AND METHODS FOR TREATING MAST-CELL MEDIATED CONDITIONS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995032945-A1 | COMPOSITIONS AND METHODS FOR TREATING MAST-CELL MEDIATED CONDITIONS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1995-12-07 | — | — | WO | disclosed |