Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29106487 | 0.89 | TSHR (0.34) | CYP1A2MEN1CYP2C9KMT2A | |
| SCHEMBL5033288 | 0.72 | GAA (0.41) | CYP1A2MEN1KMT2A | |
| SCHEMBL6689900 | 0.68 | CYP2C9 (0.47) | CYP1A2MEN1CYP2C9KMT2A | |
| SCHEMBL8749499 | 0.68 | — | — | |
| SCHEMBL7127124 | 0.67 | MAPT (0.34) | — | |
| SCHEMBL13745023 | 0.65 | OPRM1 (0.37) | — | |
| SCHEMBL11616225 | 0.64 | CYP1A2 (0.35) | CYP1A2 | |
| SCHEMBL6189894 | 0.61 | OPRM1 (0.39) | CYP1A2MEN1KMT2A | |
| SCHEMBL6253537 | 0.61 | HDAC1 (0.42) | CYP1A2 | |
| SCHEMBL17870655 | 0.61 | OPRM1 (0.34) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416038-B1 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED | TROPIX INC (US) | 1997-03-26 | — | — | EP | claimed |
| EP-0416038-A4 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED | — | 1992-02-26 | — | — | EP | claimed |
| EP-0416038-A1 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED. | TROPIX INC (US) | 1991-03-13 | — | — | EP | claimed |
| WO-1990000164-A1 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED | TROPIX, INC. (US) | 1990-01-11 | — | — | WO | claimed |
| CN-109996560-A | Antibodies that bind to Zika virus envelope protein and uses thereof | 麻省理工学院 | 2019-07-09 | — | — | CN | disclosed |
| CN-107406494-A | Novel PD-L1 binding polypeptides for imaging | 百时美施贵宝公司 | 2017-11-28 | — | — | CN | disclosed |
| CN-107278206-A | Antibodies that bind to human C6 and uses thereof | 雷根尼桑斯公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-106999566-A | Antibodies that bind to ebola virus glycoprotein and uses thereof | 麻省理工学院 | 2017-08-01 | — | — | CN | disclosed |
| EP-0416038-B1 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED | TROPIX INC (US) | 1997-03-26 | — | — | EP | disclosed |