Acrylic Acid Methyl Ester

Acrylic Acid Methyl Ester

SCHEMBL8749697

C=C(Cl)Cl.C=CC(=O)O.C=CC(=O)OC

nearest known ligand 0.46

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
HCAR2 Q8TDS4 2/20 0.44
HSD17B10 Q99714 3/20 0.40
ALOX15 P16050 2/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
TSHR P16473 6/20 0.34
ALDH1A1 P00352 7/20 0.33
HPGD P15428 1/20 0.33
RECQL P46063 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL11701869 0.93 HCAR2 (0.46) LMNAHCAR2HSD17B10KEAP1NFE2L2
Acrylic Acid Methyl Ester SCHEMBL271559 0.93 HCAR2 (0.46) LMNAHCAR2HSD17B10KEAP1NFE2L2
Acrylic Acid Methyl Ester SCHEMBL28195282 0.91 LMNA (0.56) LMNAHCAR2HSD17B10ALOX15KEAP1
Acrylic Acid Methyl Ester SCHEMBL27888603 0.91 LMNA (0.56) LMNAHCAR2HSD17B10ALOX15KEAP1
Acrylic Acid Methyl Ester SCHEMBL36950 0.91 LMNA (0.56) LMNAHCAR2HSD17B10ALOX15KEAP1
Acrylic Acid Methyl Ester SCHEMBL9453514 0.89 ALDH1A1 (0.54) LMNAHCAR2HSD17B10ALOX15KEAP1
Acrylic Acid Methyl Ester SCHEMBL18240069 0.88 HCAR2 (0.42) HCAR2HSD17B10KEAP1NFE2L2TSHR
Acrylic Acid Methyl Ester SCHEMBL9473441 0.88 LMNA (0.53) LMNAHCAR2HSD17B10ALOX15KEAP1
Acrylic Acid Methyl Ester SCHEMBL28428357 0.88 LMNA (0.53) LMNAHCAR2HSD17B10ALOX15KEAP1
Acrylic Acid Methyl Ester SCHEMBL9182225 0.88 LMNA (0.53) LMNAHCAR2HSD17B10ALOX15KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0554000-B1 A black-and-white silver halide photographic light-sensitive material and a method for processing the same KONISHIROKU PHOTO IND (JP) 1997-03-19 EP disclosed
US-5376509-A Comprising cyclodextrin compounds and devloper; storage stable KONICA CORPORATION (JP) 1994-12-27 US disclosed
US-5352563-A At least one of emulsion and protective layers contains a cyclodextrin compound; hydrazine derivative or tetrazolium salt in emulsion layer KONICA CORPORATION (JP) 1994-10-04 US disclosed
EP-0554000-A1 A black-and-white silver halide photographic light-sensitive material and a method for processing the same KONICA CORPORATION (JP) 1993-08-04 EP disclosed
US-5219718-A SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1993-06-15 US disclosed
US-H1063-H Containing hydrazine compound for high contrast image by fast processing KONICA CORPORATION, A CORP. OF JAPAN (JP) 1992-06-02 US disclosed
EP-0383283-A2 Silver halide photographic lightsensitive material KONICA CORPORATION (JP) 1990-08-22 EP disclosed
EP-0368229-A2 Negative type light-sensitive halide photographic material KONICA CORPORATION (JP) 1990-05-16 EP disclosed
US-4859564-A Color diffusion transfer photographic element with reducing sugar FUJI PHOTO FILM CO., LTD. (JP) 1989-08-22 US disclosed