SCHEMBL8749720

SCHEMBL8749720

CC(C)(C)C1=CC(=O)C(c2ccccc2)=CC1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 7/20 0.53
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
PTPN1 P18031 4/20 0.44
PTPRC P08575 1/20 0.44
PTPRF P10586 1/20 0.44
CDC25B P30305 1/20 0.44
HSD17B3 P37058 1/20 0.44
PDE4B Q07343 1/20 0.42
MAPT P10636 3/20 0.37
LMNA P02545 2/20 0.37
HTT P42858 2/20 0.37
KMT2A Q03164 2/20 0.37
POLB P06746 1/20 0.36
GPR55 Q9Y2T6 1/20 0.36
HK2 P52789 1/20 0.36
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
ATM Q13315 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoquinone SCHEMBL28071172 0.93 MAOA (0.55) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL28071173 0.86 MAOA (0.59) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL22203779 0.81 BACE1 (0.46) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL221295 0.81 BACE1 (0.65) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL49783 0.76 MAPT (0.50) MAPTLMNAHTTKMT2APOLB
SCHEMBL25834271 0.74 BACE1 (0.53) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL28029389 0.73 MAPT (0.48) MAPTLMNAHTTKMT2APOLB
SCHEMBL12480578 0.71 BACE1 (0.60) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL22203772 0.71 BACE1 (0.55) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL11229393 0.69 BACE1 (0.53) BACE1MAOAMAOBPTPN1PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021162115-A1 LAMINATE, DISPLAY DEVICE, AND ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE 富士フイルム株式会社 2021-08-19 WO disclosed
EP-0523470-B1 Complexed hydroquinones POLAROID CORP (US) 1997-03-19 EP disclosed
US-5338644-A Form complexes with N,N,N*,N*-tetrasubstituted diamides of aromatic dicarboxylic acids to prevent migration of hydroquinones puring storage POLAROID CORPORATION (US) 1994-08-16 US disclosed
EP-0523470-A2 Complexed hydroquinones POLAROID CORPORATION (US) 1993-01-20 EP disclosed
US-5177262-A Hydrogen-Bonded Complex with N,N,N',N'-Tetrasubstituted P-Aromatic Dicarboxamides POLAROID CORPORATION (US) 1993-01-05 US disclosed